TABLE 5

α7 nAChR-associated diseases

DiseaseReference
Auditory dating deficits in families with schizophrenia and smokers with schizophreniaFreedman et al., 1996; Leonard et al., 2002; Gault et al., 2003; Mexal et al., 2010; Flomen et al., 2013
Triplication in three generation pedigree of cognitive impairment and neuropsychiatric phenotypeSoler-Alfonso et al., 2014
Inherited phenotypic trait of schizophreniaAdler et al., 1998
Neuropsychiatric disordersRiley et al., 2002
EpilepsyElmslie et al., 1997; Rozycka et al., 2013
AD susceptibility; MCI risk and conversion to ADBarabash et al., 2009; Heinzen et al., 2010; Swaminathan et al., 2011, 2012a,b
AD, Dementia with DLB or Pick'sFeher et al., 2009
Benign rolendic epilepsyNeubauer et al., 1998
Autism and Rett SyndromeAllen-Brady et al., 2010; Yasui et al., 2011
Developmental Delay, Mental Retardation and/or ASDMikhail et al., 2011
Microdeletion SyndromeMasurel-Paulet et al., 2010; Szafranski et al., 2010