Mammalian Toll-like receptor families
Mammalian TLRs are grouped into six major families based on amino acid similarity, genomic structure and ligand properties. TLR10 is a pseudogene.
| TLR Family | |
|---|---|
| 1 | TLR1, TLR2, TLR6, TLR10 |
| 3 | TLR3 |
| 4 | TLR4 |
| 5 | TLR5 |
| 7 | TLR7, TLR8, TLR9 |
| 11 | amTLR11, mTLR12, mTLR13 |
↵a Letter “m” preceding some TLRs indicate “mouse.” The remaining TLRs are shared by all mammals.