Effects of CETP inhibitors on plasma lipids and lipoproteins
Data are given as the effect on concentration with percentages in parentheses.
| CETP Inhibitor | HDL-C | ApoA-I | LDL-C | ApoB | Lp(a) |
|---|---|---|---|---|---|
| Torcetrapib | Increase (72) | Increase (25) | Decrease (24) | Decrease (13) | Not available |
| Dalcetrapib | Increase (30) | Increase (10) | No change | No change | Not available |
| Anacetrapib | Increase (140) | Increase (45) | Decrease (30) | Decrease (21) | Decrease (39) |
| Evacetrapib | Increase (130) | Increase (40) | Decrease (30) | Decrease (25) | Not available |
| TA-8995 | Increase (180) | Increase (60) | Decrease (45) | Decrease (35) | Decrease (35) |