Gene list and descriptions from DAVID bioinformatics database (

No.NameFull NameDescriptionReference
1BOCBOC cell adhesion associated, oncogene regulatedComponent of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cellsTenzen et al. (2006)
2CLEC4GP1C-type lectin domain family 4 member G pseudogene 1Function unknown
3ELOVL6ELOVL fatty acid elongase 6Fatty acid elongase specific to C12-C16 saturated and monounsaturated fatty acidsFeng et al. (2016)
4EREGepiregulinMay be a mediator of localized cell proliferationRiese and Cullum (2014)
5ESR2estrogen receptor 2Nuclear hormone receptor that binds estrogens with an affinity similar to that of ESR1 and activates expression of reporter genes containing estrogen response elements in an estrogen-dependent mannerBatistatou et al. (2004), Sareddy et al. (2016)
6FDCSPfollicular dendritic cell secreted proteinCan bind to the surface of B-lymphoma cells, but not T-lymphoma cells, consistent with a function as a secreted mediator acting upon B-cellsWang et al. (2010), Hou et al. (2014)
7FURINfurin, paired basic amino acid cleaving enzymeRelease of mature proteins from their proproteins by cleavage of -Arg-Xaa-Yaa-Arg-|-Zaa- bonds, where Xaa can be any amino acid and Yaa is Arg or Lys and regulates TGF-β bioavailabilityPhillips-Mason et al. (2014)
8FUT8-AS1fucosyltransferase 8 antisense RNA 1Fucosylation of proteins, including EGFRLiu et al. (2011)
9GZMBgranzyme BThis enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. It has been associated with both tumor progression and regression, in a case-dependent manner.Medema et al. (2001), Rousalova and Krepela (2010)
10IRX3iroquois homeobox 3Belongs to the TALE/IRO homeobox family and may have a direct functional relationship to both obesity and type 2 diabetes. IRX3 is a proneural gene important for neuronal differentiation.Yang et al. (2010), Seol et al. (2011)
11LITAFlipopolysaccharide induced TNF factorProbable role in regulating transcription of specific genes. May regulate through NF-κB1 the expression of the CCL2/MCP-1 chemokine. May play a role in TNF-alpha gene expression.Zou et al. (2015)
12NDEL1nudE neurodevelopment protein 1 like 1Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL. Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome.Hong et al. (2016)
13NKX3-1NK3 homeobox 1Transcription factor, which binds preferentially the consensus sequence 5′-TAAGT[AG]-3′ and can behave as a transcriptional repressor. Could play an important role in regulating proliferation of glandular epithelium and in the formation of ducts in prostate.Bhatia-Gaur et al. (1999)
14PODNL1podocan like 1Belongs to the small leucine-rich proteoglycan (SLRP) familyHeyn et al. (2013), Yan et al. (2013), Teng and Zheng (2017)
15PTPRNprotein tyrosine phosphatase, receptor type NImplicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions.Xie et al. (1996), Bauerschlag et al. (2011)
16QSOX1quiescin sulfhydryl oxidase 1Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide. May contribute to disulfide bond formation in a variety of secreted proteins.Katchman et al. (2011)
17SEMA4Fsemaphorin 4FEstrogen-regulated semaphorin ligand with growth cone collapse activity against retinal ganglion-cell axonsParrinello et al. (2008)
18THtyrosine hydroxylasePlays an important role in the physiology of adrenergic neuronsTekin et al. (2014)
19VEGFCvascular endothelial growth factor CGrowth factor active in angiogenesis and endothelial cell growth, stimulating proliferation and migration. Has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and in the maintenance of differentiated lymphatic endothelium in adults.Denicolaï et al. (2016), Dufies et al. (2017)
20C20orf166AS1chromosome 20 open reading frame 166 antisense RNA 1Long noncoding RNAHu et al. (2014)
  • TNF, tumor necrosis factor.