Sequences of human receptors were aligned using the BLAST algorithm, and the percentages of sequence identity (upper right) and similarity (i.e., the presence of similar amino acids; lower left) were determined
Sequence comparisons are limited to the core regions of receptors (i.e., sequences encompassing the seven-helix bundle plus adjacent segments), whereas no significant similarities were detected in the N-terminal and C-terminal tails.
SST1 | SST2 | SST3 | SST4 | SST5 | |
---|---|---|---|---|---|
SST1 | 100 | 55 | 52 | 69 | 49 |
SST2 | 74 | 100 | 53 | 53 | 56 |
SST3 | 69 | 69 | 100 | 48 | 56 |
SST4 | 82 | 73 | 66 | 100 | 53 |
SST5 | 64 | 74 | 69 | 70 | 100 |