TABLE 1

Studies examining the effects of MDMA on attention

ArticleTaskaSubjectsbDoses/FrequencycTimelinedEffectse
Taffe et al., 20015-CSRTMonkeys (R), Adult, Male10 mg/kg (i.m.) × 2/day, 4 daysTraining: Predrug Testing: On-Drug, Postdrug↓ (On-Drug), ⌀ (Postdrug)
Taffe et al., 20025-CSRTMonkeys (R), Adult, Male10 mg/kg (i.m.) × 2/day, 4 daysTraining: Predrug Testing: Postdrug
  • a Studies used the 5-choice serial reaction time (5-CSRT) task.

  • b Species (strain), age, and sex of subjects. Strains include rhesus (R) monkeys.

  • c Dose, route, and frequency of MDMA administration. Treatment days/weeks are consecutive unless noted as “spaced.”

  • d When training and testing occurred in relation to drug treatment. Pre- and post-drug training/testing were always conducted off-drug.

  • e Effects of drug treatment on attention: ⌀ No Effect, ↓ Impairment, ↑ Enhancement.