Expression of apelin receptor (APLNR), apelin, and ELA in mouse, rat, and human tissues
Compiled from Edinger et al. (1998), Hosoya et al. (2000), Lee et al. (2000), O’Carroll et al. (2000), Medhurst et al. (2003), Kleinz and Davenport (2005), Regard et al. (2008), Pope et al. (2012), Deng et al. (2015), Wang et al. (2015b).
APLNR | Apelin | ELA | |||||||
---|---|---|---|---|---|---|---|---|---|
Human | Rat | Mouse | Human | Rat | Mouse | Human | Rat | Mouse | |
Brain | +++ | ++ | + | ++ | + | +++ | |||
-paraventricular nucleus | + | ++ | |||||||
-supraoptic nucleus | ++ | ++ | |||||||
Anterior pituitary | +a | +++ | +++ | ++a | +a | ||||
Intermediate pituitary | −/+ | −/+ | +/+++ | ||||||
Posterior pituitary | −/+ | −/++ | +/++ | ||||||
Thymus | + | − | + | − | |||||
Spinal cord | + | +++ | ++ | ++ | ++ | ||||
Cerebellum | + | + | − | + | + | − | |||
Hippocampus | + | + | − | + | + | ||||
Thalamus | + | + | + | + | |||||
Heart | + | ++ | +++ | + | ++ | ++ | −/+ | + | |
Adrenal gland | + | + | + | ||||||
Lungs | ++ | +++ | ++ | + | +++ | ++ | + | ||
Stomach | + | + | + | − | + | ||||
Liver | + | − | + | − | − | − | |||
Small intestine | ++ | + | + | − | + | ||||
Large intestine | ++ | + | + | + | |||||
Pancreas | + | − | + | + | |||||
Kidney | + | + | + | + | + | + | ++ | +++ | |
Testis | + | + | + | + | + | ++ | |||
Prostate | + | + | ++ | ||||||
Ovary | + | + | ++ | + | + | ||||
Uterus | + | + | ++ | − | + | − | |||
Placenta | ++ | ++ | ++ | ||||||
Mammary gland | + | ++ | |||||||
Skeletal muscle | + | ++ | ++ | − | + | + | |||
Adipose tissue | ++ | ++ | ++b | ++ | |||||
Cartilage | ++ | ++ | |||||||
Spleen | +++ | − | + | − | + | ||||
Skin | + | + | |||||||
Bladder | + | + | |||||||
Gall bladder | + |