TABLE 4

Overview of microRNAs enhancing or reducing ABCA1 and ABCG1 mRNA

Overview of microRNAs, including their effects on ABCA1 and ABCG1 expression. Effects on ABCA1, ABCG1, and cholesterol efflux are presented as follows: (↓) decreased; (= ) no effect; (↑) increased.

MicroRNAABCA1ABCG1Reference
miR-10bHazen and Smith, 2012; Wang et al., 2012; Dávalos and Fernandez-Hernando, 2013; Goedeke et al., 2014; Rayner and Moore, 2014; Rotllan et al., 2016; Aryal et al., 2017
miR-17He et al., 2015
miR-19bLv et al., 2014, 2015; DiMarco and Fernandez, 2015
miR-20a/bLiang et al., 2017
miR-21Canfrán-Duque et al., 2017
miR-26↓ (Indirect via LXR)Sun et al., 2012; Dávalos and Fernandez-Hernando, 2013; Canfrán-Duque et al., 2014; Goedeke et al., 2014; Rayner and Moore, 2014; DiMarco and Fernandez, 2015; Yang et al., 2015; Feinberg and Moore, 2016; Rotllan et al., 2016
miR-27a/b= (↓ Indirect)Kang et al., 2013; Canfrán-Duque et al., 2014; Goedeke et al., 2014, 2015b; Zhang et al., 2014; DiMarco and Fernandez, 2015; Yang et al., 2015; Rotllan et al., 2016
miR-33a/33bMoore et al., 2010, 2011; Fernandez-Hernando et al., 2011; Fernández-Hernando and Moore, 2011; Rayner et al., 2011, 2012; Iatan et al., 2012; Rotllan and Fernandez-Hernando, 2012; Dávalos and Fernandez-Hernando, 2013; Kang et al., 2013; Canfrán-Duque et al., 2014; Goedeke et al., 2014; Mao et al., 2014; Rayner and Moore, 2014; DiMarco and Fernandez, 2015; He et al., 2015; Mandolini et al., 2015; Yang et al., 2015; Feinberg and Moore, 2016; Ono, 2016; Rotllan et al., 2016; Aryal et al., 2017
miR-93He et al., 2015
miR-96Moazzeni et al., 2017
miR-101Zhang et al., 2015a; Aryal et al., 2017
miR-106bKim et al., 2012; Rotllan and Fernandez-Hernando, 2012; Dávalos and Fernandez-Hernando, 2013; Goedeke et al., 2014; Rayner and Moore, 2014; Feinberg and Moore, 2016
miR-128-1Wagschal et al., 2015; Feinberg and Moore, 2016; Rotllan et al., 2016; Aryal et al., 2017
miR-128-2Adlakha et al., 2013; DiMarco and Fernandez, 2015
miR-130bWagschal et al., 2015; Feinberg and Moore, 2016
miR-144↓ (Indirect via RXR)de Aguiar Vallim et al., 2013; Kang et al., 2013; Ramírez et al., 2013; Canfrán-Duque et al., 2014; Goedeke et al., 2014; Rayner and Moore, 2014; DiMarco and Fernandez, 2015; Feinberg and Moore, 2016; Rotllan et al., 2016; Aryal et al., 2017
miR-145Kang et al., 2013; Canfrán-Duque et al., 2014; Goedeke et al., 2014; Sala et al., 2014; DiMarco and Fernandez, 2015
miR-148aKang et al., 2013; Goedeke et al., 2015a; Wagschal et al., 2015; Feinberg and Moore, 2016; Rotllan et al., 2016; Aryal et al., 2017
miR-223DiMarco and Fernandez, 2015; Rotllan et al., 2016
miR-301bWagschal et al., 2015; Feinberg and Moore, 2016
miR-302aDiMarco and Fernandez, 2015; Meiler et al., 2015; Rotllan et al., 2016; Aryal et al., 2017
miR-378↓ (Indirect)Wang et al., 2014a; DiMarco and Fernandez, 2015; Yang et al., 2015
miR-613Zhao et al., 2014; DiMarco and Fernandez, 2015
miR-758Ramirez et al., 2011; Kim et al., 2012; Rayner et al., 2012; Rotllan and Fernandez-Hernando, 2012; Dávalos and Fernandez-Hernando, 2013; Canfrán-Duque et al., 2014; Goedeke et al., 2014; Rayner and Moore, 2014; DiMarco and Fernandez, 2015; Mandolini et al., 2015; Yang et al., 2015; Feinberg and Moore, 2016
  • miR, microRNA.