Overview of microRNAs enhancing or reducing ABCA1 and ABCG1 mRNA
Overview of microRNAs, including their effects on ABCA1 and ABCG1 expression. Effects on ABCA1, ABCG1, and cholesterol efflux are presented as follows: (↓) decreased; (= ) no effect; (↑) increased.
| MicroRNA | ABCA1 | ABCG1 | Reference |
|---|---|---|---|
| miR-10b | ↓ | ↓ | Hazen and Smith, 2012; Wang et al., 2012; Dávalos and Fernandez-Hernando, 2013; Goedeke et al., 2014; Rayner and Moore, 2014; Rotllan et al., 2016; Aryal et al., 2017 |
| miR-17 | ↓ | He et al., 2015 | |
| miR-19b | ↓ | Lv et al., 2014, 2015; DiMarco and Fernandez, 2015 | |
| miR-20a/b | ↓ | Liang et al., 2017 | |
| miR-21 | ↓ | ↓ | Canfrán-Duque et al., 2017 |
| miR-26 | ↓ | ↓ (Indirect via LXR) | Sun et al., 2012; Dávalos and Fernandez-Hernando, 2013; Canfrán-Duque et al., 2014; Goedeke et al., 2014; Rayner and Moore, 2014; DiMarco and Fernandez, 2015; Yang et al., 2015; Feinberg and Moore, 2016; Rotllan et al., 2016 |
| miR-27a/b | ↓ | = (↓ Indirect) | Kang et al., 2013; Canfrán-Duque et al., 2014; Goedeke et al., 2014, 2015b; Zhang et al., 2014; DiMarco and Fernandez, 2015; Yang et al., 2015; Rotllan et al., 2016 |
| miR-33a/33b | ↓ | ↓ | Moore et al., 2010, 2011; Fernandez-Hernando et al., 2011; Fernández-Hernando and Moore, 2011; Rayner et al., 2011, 2012; Iatan et al., 2012; Rotllan and Fernandez-Hernando, 2012; Dávalos and Fernandez-Hernando, 2013; Kang et al., 2013; Canfrán-Duque et al., 2014; Goedeke et al., 2014; Mao et al., 2014; Rayner and Moore, 2014; DiMarco and Fernandez, 2015; He et al., 2015; Mandolini et al., 2015; Yang et al., 2015; Feinberg and Moore, 2016; Ono, 2016; Rotllan et al., 2016; Aryal et al., 2017 |
| miR-93 | ↓ | He et al., 2015 | |
| miR-96 | ↓ | Moazzeni et al., 2017 | |
| miR-101 | ↓ | Zhang et al., 2015a; Aryal et al., 2017 | |
| miR-106b | ↓ | Kim et al., 2012; Rotllan and Fernandez-Hernando, 2012; Dávalos and Fernandez-Hernando, 2013; Goedeke et al., 2014; Rayner and Moore, 2014; Feinberg and Moore, 2016 | |
| miR-128-1 | ↓ | Wagschal et al., 2015; Feinberg and Moore, 2016; Rotllan et al., 2016; Aryal et al., 2017 | |
| miR-128-2 | ↓ | ↓ | Adlakha et al., 2013; DiMarco and Fernandez, 2015 |
| miR-130b | ↓ | Wagschal et al., 2015; Feinberg and Moore, 2016 | |
| miR-144 | ↓ | ↓ (Indirect via RXR) | de Aguiar Vallim et al., 2013; Kang et al., 2013; Ramírez et al., 2013; Canfrán-Duque et al., 2014; Goedeke et al., 2014; Rayner and Moore, 2014; DiMarco and Fernandez, 2015; Feinberg and Moore, 2016; Rotllan et al., 2016; Aryal et al., 2017 |
| miR-145 | ↓ | Kang et al., 2013; Canfrán-Duque et al., 2014; Goedeke et al., 2014; Sala et al., 2014; DiMarco and Fernandez, 2015 | |
| miR-148a | ↓ | Kang et al., 2013; Goedeke et al., 2015a; Wagschal et al., 2015; Feinberg and Moore, 2016; Rotllan et al., 2016; Aryal et al., 2017 | |
| miR-223 | ↑ | DiMarco and Fernandez, 2015; Rotllan et al., 2016 | |
| miR-301b | ↓ | Wagschal et al., 2015; Feinberg and Moore, 2016 | |
| miR-302a | ↓ | DiMarco and Fernandez, 2015; Meiler et al., 2015; Rotllan et al., 2016; Aryal et al., 2017 | |
| miR-378 | ↓ (Indirect) | Wang et al., 2014a; DiMarco and Fernandez, 2015; Yang et al., 2015 | |
| miR-613 | ↓ | Zhao et al., 2014; DiMarco and Fernandez, 2015 | |
| miR-758 | ↓ | Ramirez et al., 2011; Kim et al., 2012; Rayner et al., 2012; Rotllan and Fernandez-Hernando, 2012; Dávalos and Fernandez-Hernando, 2013; Canfrán-Duque et al., 2014; Goedeke et al., 2014; Rayner and Moore, 2014; DiMarco and Fernandez, 2015; Mandolini et al., 2015; Yang et al., 2015; Feinberg and Moore, 2016 |
miR, microRNA.