Tissue and subcellular distribution of monocarboxylate transporters
Transporter | Unigene Name | Tissue Distribution | Subcellular Localization | Expression | Species | References |
---|---|---|---|---|---|---|
MCT1 | SLC16A1 | Ubiquitous | Apical and basolateral membrane | Human | Halestrap and Meredith, 2004; Gill et al., 2005 | |
MCT2 | SLC16A7 | Liver | Basolateral membrane | Protein | Human | Garcia et al., 1994; Lin et al., 1998; Halestrap and Meredith, 2004; Wilson et al., 2005; Becker et al., 2010b |
Kidney | Basolateral membrane | Protein | Human | |||
Apical | Mouse | |||||
Skeletal muscle | Protein | Human | ||||
Heart | Protein | Human | ||||
Brain | Protein | Human | ||||
Spleen | Protein | Human | ||||
Testis | Basolateral membrane | Protein | Human | |||
Pancreas | Protein | Human | ||||
MCT3 | SLC16A8 | Retinal pigment epithelium | Basolateral membrane | Halestrap and Meredith, 2004 | ||
MCT4 | SLC16A3 | Kidney | Basolateral membrane | Protein | Human | Dimmer et al., 2000; Halestrap and Meredith, 2004; Settle et al., 2004; Gill et al., 2005; Wang et al., 2006b |
Skeletal muscle | Protein | Human | ||||
Intestine | Basolateral membrane | Protein | Human | |||
Heart | Protein | Human | ||||
Lung | Protein | Human | ||||
MCT5 | SLC16A4 | Liver | mRNA | Rat | Felmlee | |
Kidney | mRNA | Rat | ||||
MCT6 | SLC16A5 | Kidney | mRNA | Rat | Felmee | |
Intestine | Basolateral membrane | Protein | Human | Gill et al., 2005 | ||
MCT7 | SLC16A6 | Kidney | mRNA | Rat | Felmlee | |
MCT8 | SLC16A2 | Liver | Sinusoidal membrane | mRNA | Human, Rat | Bonen et al., 2006; Nishimura and Naito, 2008; Roberts et al., 2008 |
Kidney | Basolateral membrane (proximal tubule) | mRNA | Human, Rat | Felmlee | ||
Adrenal gland | mRNA | Human | ||||
Brain (neurons, blood brain barrier) | mRNA | Human | ||||
Choroid plexus | Apical membrane | Protein | Human | |||
Mouse | ||||||
Ovary | mRNA | Human | ||||
Thyroid gland | mRNA | Human | ||||
Uterus | mRNA | Human | ||||
Placenta | mRNA | Human | ||||
Heart | mRNA | Human | ||||
Protein | Rat | |||||
Lung | mRNA | Rat | ||||
MCT10 | SLC16A10 | Liver | mRNA | Rat | Felmlee | |
Kidney | mRNA | Rat | ||||
Intestine | mRNA | Rat | ||||
Lung | mRNA | Rat | ||||
MCT11 | SLC16A11 | Liver | mRNA | Rat | Felmlee | |
Kidney | mRNA | Rat | ||||
Lung | mRNA | Rat | ||||
MCT12 | SLC16A12 | Liver | mRNA | Rat | Felmlee | |
Kidney | mRNA | Rat | ||||
Lung | mRNA | Rat | ||||
MCT13 | SLC16A13 | Liver | mRNA | Rat | Felmlee | |
Kidney | mRNA | Rat | ||||
Intestine | mRNA | Rat | ||||
Lung | mRNA | Rat | ||||
MCT14 | SLC16A14 | Peripheral blood mononuclear cells | mRNA | Human | Banerjee et al., 2017 | |
Kidney | mRNA | Rat | Felmlee |