Human | Rat | Mouse | References | |
---|---|---|---|---|
EP1 Receptor | ||||
Gene symbol | PTGER1 | Ptger1 | Ptger1 | Funk et al., 1993; Watabe et al., 1993; Båtshake et al., 1995; Ishikawa et al., 1996; Okuda-Ashitaka et al., 1996; Boie et al., 1997 |
Gene ID | 5731 | 25637 | 19216 | |
Chromosomal location | 19p13.12 | 19q11 | 8 C2 | |
Number of exons | 3 | 3 | 3 | |
Number of amino acids | 402 | 405 Variant 366 | 405 | |
EP2 receptor | ||||
Gene symbol | PTGER2 | Ptger2 | Ptger2 | Regan et al., 1994b; Katsuyama et al., 1995; Boie et al., 1997; Nemoto et al., 1997; Smock et al., 1999 |
Gene ID | 5732 | 81752 | 19217 | |
Chromosomal location | 14q22.1 | 15p14 | 14 C1 | |
Number of exons | 2 | 3 | 3 | |
Number of amino acids | 358 | 357 | 362 | |
EP3 receptora | ||||
Gene symbol | PTGER3 | Ptger3 | Ptger3 | Sugimoto et al., 1992, 1993; Irie et al., 1993; Takeuchi et al., 1993, 1994; Neuschäfer-Rube et al., 1994; Regan et al., 1994a; Kotani et al., 1995; Schmid et al., 1995; Boie et al., 1997; Kotani et al., 1997; Oldfield et al., 2001; Bilson et al., 2004 |
Gene ID | 5733 | 24929 | 19218 | |
Chromosomal location | 1p31.1 | 2q45 | 3 H4 | |
Number of exons | 10 | 4 | 4 | |
Protein derived from splicing variants (UniProtKB accession number) and number of amino acids | EP3-I (P43115-1) 390 | EP3α 365 | EP3α 365 | |
EP3-II (P43115-2) 388 | EP3β 361 | EP3β 361 | ||
EP3-III (P43115-3) 365 | EP3γ 364 | EP3γ 364 | ||
EP3-IV (P43115-4) 374 | EP3δ 343 | |||
EP3-e (P43115-5) 418b | ||||
EP4 receptor | ||||
Gene symbol | PTGER4 | Ptger4 | Ptger4 | (An et al., 1993; Honda et al., 1993; Bastien et al., 1994; Sando et al., 1994)c; Arakawa et al., 1996; Boie et al., 1997 |
Gene ID | 5734 | 84023 | 19219 | |
Chromosomal location | 5p13.1 | 2q16 | 15 A1 | |
Number of exons | 7 | 3 | 3 | |
Number of amino acids | 488 | 488 | 513 | |
IP receptor | ||||
Gene symbol | PTGIR | Ptgir | Ptgir | Boie et al., 1994; Nakagawa et al., 1994; Namba et al., 1994; Sasaki et al., 1994 |
Gene ID | 5739 | 292661 | 19222 | |
Chromosomal location | 19q13.32 | 1q21 | 7 A2 | |
Number of exons | 6 | 2 | 2 | |
Number of amino acids | 386 | 416 | 415 |
↵a Ten transcripts produced by alternative splicing in human have been detected for the EP3 receptor. Here are presented the five human EP3 protein isoforms mostly found.
↵b Correct value for EP3e amino-acid number, which has been described with mistake starting after Leu 373 in Schmid et al. (1995), Kotani et al. (1997), Lebender et al. (2018).
↵c These publications present data for EP4 receptors under wrong nomenclature of EP2 receptors.