TABLE 3

Products, inhalers, and characteristics of short-acting β2 adrenoceptor agonists

Active IngredientIndicationInhalerDosePharmacological ProfileClinical Summary
Epinephrin (adrenaline)Acute relief of asthma symptoms not for chronic usepMDI125 µg/puff, two puffsα and β adrenoceptor agonist rapid onset
<5 min short duration <30 min
Only indicated for short-term rescue use
Albuterol (salbutamol)Bronchospasm of any causepMDI
Nebulizer solution DPI
100 µg/puff, two puffs
2.5 mg
100 µg or 200
µg/actuation
β2 adrenoceptor agonist rapid onset
<5 min and short duration <4 h
Short-term rescue or prevention of exercise-induced asthma
Acute bronchospasm not responding to other delivery
Short-term rescue or prevention of exercise-induced asthma
TerbutalineBronchospasm of any causeDPI
Nebulizer solution
500 µg/puff; one puff
2.5 mg solution
β2 adrenoceptor agonist rapid onset
<5 min and short duration <4 h
Short-term rescue or prevention of exercise-induced asthma
Acute bronchospasm not responding to other delivery
LevalbuterolBronchospasm of any causepMDI
Nebulizer solution
50 µg/puff; two puffs
31 to 125 μg
β2 adrenoceptor agonist rapid onset
<5 min and short duration <4 h
Short-term rescue or prevention of exercise-induced asthma
Acute bronchospasm not responding to other delivery
FenoterolBronchospasm of any causeDPI
Nebulizer solution
12 µg/capsule
20 μg
β2 adrenoceptor agonist rapid onset
<5 min and short duration <6 h
Short-term rescue or prevention of exercise-induced asthma