TABLE 6

Table with strengths/weaknesses of skeletal muscle models

Pluripotent Stem CellsPrimary MyoblastsMature Myofiber Cultures
Maturation methodTransgene- or small molecule-basedTransgene- or small molecule–basedNot applicable
Phenotype++++++
Length of differentiation protocol+++Not applicable
Stability in culture++++++
Accessibility++++++
Homogeneity of culture++++++
Functionality++++++
Current use in drug testing+++++Not tested yet