Table with strengths/weaknesses of skeletal muscle models
Pluripotent Stem Cells | Primary Myoblasts | Mature Myofiber Cultures | |
---|---|---|---|
Maturation method | Transgene- or small molecule-based | Transgene- or small molecule–based | Not applicable |
Phenotype | + | ++ | +++ |
Length of differentiation protocol | + | ++ | Not applicable |
Stability in culture | +++ | ++ | + |
Accessibility | +++ | ++ | + |
Homogeneity of culture | + | ++ | +++ |
Functionality | + | ++ | +++ |
Current use in drug testing | +++ | ++ | Not tested yet |