Biochemical and Biophysical Research Communications
Regular ArticleThe Hepatocyte Nuclear Factor 4 (HNF-4) Represses the Mitochondrial HMG-CoA Synthase Gene☆
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Chicken ovalbumin upstream promoter-transcription factor I represses the transcriptional activity of the human muscle glycogen phosphorylase promoter in C2C12 cells
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The abbreviations used are: HMG-CoA, 3-hydroxy-3-methylglutaryl-CoA; CAT, chloramphenicol acetyltransferase; COUP-TF, chicken ovalbumin upstream promoter transcription factor; PPAR, peroxisome proliferator-activated receptor; PPRE, peroxisome proliferator-responsive element; NRRE, nuclear receptor-responsive element; RAR, retinoic acid receptor; TR thyroid hormone receptor; HNF-4, hepatic nuclear factor 4; hRXRα, human 9-cis-retinoic acid receptor α; mPPARα, mouse peroxisome proliferator-activated receptor α; EMSA, electrophoretic mobility shift analysis
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Present address: Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas 75235.
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Present address: IGBMC. CNRS INSERM. Université Louis Pasteur. C.U. de Strasbourg, France.
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To whom correspondence should be addressed: Unitat de Bioquı́mica, Facultat de Farmàcia, Avda. Diagonal, 643, 08028 Barcelona, Spain. E-mail: [email protected].