Biochemical and Biophysical Research Communications
Neuromedin C: A bombesin-like peptide identified in porcine spinal cord
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Gastrin-releasing peptide
2021, Handbook of Hormones: Comparative Endocrinology for Basic and Clinical ResearchCharacterization of GRP as a functional neuropeptide in basal chordate amphioxus
2020, International Journal of Biological MacromoleculesUnderstanding metal binding in neuromedin C
2020, Inorganica Chimica ActaNeuromedin: An insight into its types, receptors and therapeutic opportunities
2017, Pharmacological ReportsCitation Excerpt :Ten newer neuropeptides have been discovered being endogenous ligands for orphan GPCRs [3] “Neuromedin” one such novel discovery. Neuromedin peptides are basically divided into 4 classes (1) Bombesin comprising of Neuromedin B and Neuromedin C, (2) Kanassin comprises of Neuromedin K and Neuromedin L, (3) Neurotensin comprises of Neuromedin N, (4) Neuromedin U and Neuromedin S. Isolation of the first neuromedin took place in the 1980s from porcine spinal cord which had large amount of vasoconstrictor properties which was Neuromedin U [4–9] the first neuropeptide of all, later on its different isoforms were discovered. Neuromedin U was found in brain and periphery and has many physiological aspects which include constrictive effects on the smooth muscles, control of blood pressure, pain sensations, hunger, bone metastasis and release and regulation of hormones [10–17].
Blood-brain barrier transport kinetics of the neuromedin peptides NMU, NMN, NMB and NT
2016, Neuropharmacology