Biochemical and Biophysical Research Communications
Volume 163, Issue 3, 29 September 1989, Pages 1230-1234
New products in the hepoxilin pathway: Isolation of 11-glutathionyl hepoxilin A3 through reaction of hepoxilin A3 with glutathione S-transferase
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Cited by (25)
Pathophysiology of the hepoxilins
2015, Biochimica et Biophysica Acta - Molecular and Cell Biology of LipidsCitation Excerpt :Hepoxilin A3 is subject to metabolism through the glutathione S-transferase route as is known for the leukotrienes [112–116]. This transformation into glutathionyl hepoxilin A3 (named hepoxilin A3-C in keeping with the leukotriene nomenclature) is carried out by enzymes in the liver [26] and enzyme activity has been ascribed to isozymes containing the Yb2 subunit and not the Ya or Yc subunit [24]. Hepoxilin A3-C was formed in rat hippocampal slices in the presence of the epoxide inhibitor, TCPO thereby blocking the transformation of the hepoxilin A3 precursor into the inactive trihydroxy metabolite.
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1997, Biochimica et Biophysica Acta - Lipids and Lipid MetabolismHepoxilins: a review on their cellular actions
1994, Biochimica et Biophysica Acta (BBA)/Lipids and Lipid MetabolismInhibition of mammalian hepatic glutathione S-transferases by acetylenic fatty acids
1994, Toxicology Letters
Copyright © 1989 Published by Elsevier Inc.