Short communicationLocalisation of the multidrug resistance-associated protein, MRP, in resistant large-cell lung tumour cells
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Induction of autophagy, apoptosis and aquisition of resistance in response to piceatannol toxicity in MOLT-4 human leukemia cells
2019, Toxicology in VitroCitation Excerpt :Other efflux pumps implicated in MDR are multidrug resistance-associated protein 1 (MRP1), also referred to as ATP-binding cassette subfamily C member 1 (ABCC1) (Vasiliou et al., 2009; Zhang et al., 2015) and breast cancer resistance protein (BCRP), also known as ATP-binding cassette subfamily G member 2 (ABCG2) (Doyle and Ross, 2003; Vasiliou et al., 2009). P-gp, MRP1, and BCRP are localized predominantly in the plasma membrane, but they are also present in intracellular compartments (Barrand et al., 1995; Chu et al., 2008; Flens et al., 1996; Fu et al., 2004; Fu and Roufogalis, 2007; Maliepaard et al., 2001). These ABC transporters are found in normal tissues including the liver, intestine, kidney, and capillaries of the blood-brain barrier (Cordon-Cardo et al., 1990; Doyle et al., 1998; Flens et al., 1996; Geier et al., 2013; Huls et al., 2008).
Effect of P-glycoprotein and multidrug resistance associated protein gene expression on Tc-99m MIBI imaging in hepatocellular carcinoma
2003, Nuclear Medicine and BiologyResistance mechanisms associated with altered intracellular distribution of anticancer agents
2000, Pharmacology and TherapeuticsStructural, mechanistic and clinical aspects of MRP1
1999, Biochimica et Biophysica Acta - BiomembranesBiology of the multidrug resistance-associated protein, MRP
1996, European Journal of Cancer