The effect of tubular damage by mercuric chloride on kidney function and some urinary enzymes in the dog
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Mechanisms Involved in the Renal Handling and Toxicity of Mercury
2018, Comprehensive Toxicology: Third EditionUtility of urinary alkaline phosphatase and γ-glutamyl transpeptidase in diagnosing acute kidney injury in dogs
2017, Veterinary JournalCitation Excerpt :Since measurement of uGGT and uALP is performed using routine serum ALP and GGT assays, it is readily available, cost efficient and potentially useful in guiding therapy in practice. A number of studies have shown marked increases in the urinary activity of one or both of these enzymes in experimental canine AKI models (Ellis et al., 1973; Adelman et al., 1979; Greco et al., 1985; Rao et al., 1990; Uechi et al., 1994a; Grauer et al., 1995; Rivers et al., 1996; Clemo, 1998; Lobetti and Lambrechts, 2000; Heiene et al., 2001; Palviainen et al., 2013; Ibba et al., 2016). In particular, uGGT has been investigated extensively in aminoglycoside-induced AKI in dogs, in which it has been shown to be a sensitive, early urinary biomarker (Greco et al., 1985; Rivers et al., 1996).
Renal Handling and Toxicity of Mercury
2010, Comprehensive Toxicology, Second EditionKidney Function and Damage
2008, Clinical Biochemistry of Domestic Animals, Sixth EditionComparative biochemical effects of low doses of mercury II chloride in the F344 rat and multimammate mouse (Mastomys natalensis)
1996, Comparative Biochemistry and Physiology - C Pharmacology Toxicology and Endocrinology