Elsevier

Developmental Biology

Volume 136, Issue 1, November 1989, Pages 129-139
Developmental Biology

Full paper
Transient expression of a Ca2+-activated Cl current during development of quail sensory neurons

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Abstract

The expression of a calcium-activated chloride current (ICl(Ca)) was studied during the development of the sensory neurons of quail trigeminal ganglia. This current is expressed in 20% of the neurons by the 5th day of embryonic development; it can be found in nearly all neurons by the 7th day and subsequently disappears in half of them. Similar results were obtained with dorsal root ganglion neurons. The disappearance of ICl(Ca) in part of the sensory neurons during development is not due to a selective death of the neurons possessing this current and our results suggest that it is mediated by an interaction of the sensory neurons with their target tissue.

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  • Cited by (0)

    This research was supported by Grant 3.594.0.87 from the Swiss National Science Foundation.

    1

    Present address: Institut de Physiologie (UA 309, CNRS) Université Louis Pasteur, 67084 Strasbourg, France.

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