MinireviewExistence of antiopiate systems as illustrated by MIF-1/Tyr-MIF-1
References (74)
- et al.
Neurosci. Biobehav. Rev.
(1980) - et al.
Peptides
(1985) - et al.
Eur. J. Pharmacol.
(1975) - et al.
Prog. Neuro-psychopharmacol. and Biol. Psychiat.
(1985) - et al.
Peptides
(1981) Eur. J. Pharmacol.
(1976)- et al.
Eur. J. Pharmacol.
(1981) - et al.
Eur. J. Pharmacol.
(1982) - et al.
Life Sci.
(1977) - et al.
Pharmacol. Biochem. Behav.
(1979)
Pharmacol. Biochem. Behav.
Pharmacol. Biochem. Behav.
Pharmacol. Biochem. Behav.
Prog. Neuro-Psychopharmacol. and Biol. Psychiat.
Biochem. Biophys. Res. Commun.
Pharmacol. Biochem. Behav.
Brain Res. Bull.
Psychoneuroendocrinology
Pharmacol. Biochem. Behav.
Pharmacol. Biochem. Behav.
Brain Res. Bull.
Pharmacol. Biochem. Behav.
Pharmacol. Biochem. Behav.
Pharmacol. Biochem. Behav.
Peptides
Pharmacol. Biochem. Behav.
Life Sci.
Peptides
Pharmacol. Biochem. Behav.
Pharmacol. Biochem. Behav.
Life Sci.
Pharmacol. Biochem. Behav.
Pharmacol. Biochem. Behav.
Brain Res. Bull.
Life Sci.
Peptides
Life Sci.
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The influence of a new derivate of kisspeptin-10 – Kissorphin (KSO) on the rewarding effects of morphine in the conditioned place preference (CPP) test in male rats
2019, Behavioural Brain ResearchCitation Excerpt :Thus, KSO is a potential target for the prevention of morphine relapse. The enhanced anti-opioid activity of KSO in the model of morphine-induced CPP, in comparison with ethanol-induced CPP [30], may be due to observations that chronic opioid administration increases anti-opioid signals and may alter the balance between opioid and anti-opioid endogenous peptides [36,37]. Thus, the observed effect may be related to "up-regulation" of the number of NPFF receptors during chronic morphine administration [38].
Original endomorphin-1 analogues exhibit good analgesic effects
2017, Bioorganic and Medicinal Chemistry LettersIntracellular cAMP assay and Eu-GTP-γS binding studies of chimeric opioid peptide YFa
2011, European Journal of PharmacologyCitation Excerpt :Methionine-enkephalin-Arg6-Phe7 (MERF) peptide that belongs to the opioid family (Inturrisi et al., 1980) is comprehensively distributed in the CNS of different mammals (Majane et al., 1983). Conversely, peptides of the NPFF/FMRFa family potently antagonize morphine-induced supraspinal analgesia (Tang et al., 1984) and may function as endogenous ‘anti-opioid’ agents (Galina and Kastin, 1986). NPFF has also been perceived to exhibit opioid effects along with a role in tolerance.
Effect of chronic intra-peritoneally administered chimeric peptide of met-enkephalin and FMRFa-[d-Ala<sup>2</sup>]YFa-on antinociception and opioid receptor regulation
2010, European Journal of PainCitation Excerpt :Low affinity of NPFF/FMRFa for opioid receptors (Raffa et al., 1994) suggests distinct binding sites of these neuropeptides from those of opioids and mediate their action through own set of receptor(s)/binding sites (Allard et al., 1989). NPFF has been shown to antagonize morphine induced antinociception and that of certain endogenous opioid peptides (Yang et al., 1982; Tang et al., 1984) suggesting that NPFF/FMRFa related peptides may function as endogenous anti-opioid agents (Galina and Kastin, 1986; Goodman et al., 1995). Thus, contribute to opiate tolerance and dependence (Malin et al., 1990a,b).