Pharmacology characterization of guanine nucleotide exchange reactions in membranes from Cho cells stably transfected with human muscarinic receptors m1–m4
References (19)
Pharmacol. Ther.
(1988)- et al.
Biochem. Pharmacol.
(1990) - et al.
Eur. J. Pharmacol.
(1989) - et al.
Cell
(1989) - et al.
Mol. Pharmacol.
(1989) - et al.
Brit. J. Pharmacol.
(1959) - et al.
Mol. Pharmacol.
(1990)
Cited by (128)
Strychnine and its mono- and dimeric analogues: a pharmaco-chemical perspective
2022, Natural Product ReportsEffects of muscarinic receptor antagonists on cocaine discrimination in wild-type mice and in muscarinic receptor M<inf>1</inf>, M<inf>2</inf>, and M<inf>4</inf> receptor knockout mice
2017, Behavioural Brain ResearchCitation Excerpt :Previous investigations similarly found that the moderately M1-preferring antagonists telenzepine and trihexyphenidyl potentiated the locomotor stimulant and/or SD effects of cocaine in rats [9,34]. Tropicamide was described as somewhat M4-preferring, although recent data suggest that it is a relatively nonspecific muscarinic antagonist [35,59]. Effects of M4 receptor blockade on cocaine’s SD effects have not been reported previously, but our findings are consistent with a report that tropicamide increased or prolonged cocaine-induced stereotypies in rats [52].
The pharmacology of McN-A-343
2012, Pharmacology and TherapeuticsCitation Excerpt :Interestingly, a prototypical allosteric modulator, gallamine, inhibited McN-A-343 and Cch to a similar extent and produced a linear A–S plot with McN-A-343 (Choo et al., 1986). Pancuronium, which also may act allosterically at muscarinic M2 receptors (Leung & Mitchelson, 1982a), produced a statistically significant greater inhibition of Cch than of McN-A-343 (Choo et al., 1985). No evidence for other possibilities such as a second subtype of muscarinic receptor being present or some involvement of a non-muscarinic action of McN-A-343 (see Section 8: Non-muscarinic actions of McN-A-343) was obtained by the investigators.
Identification of an Ascaris G protein-coupled acetylcholine receptor with atypical muscarinic pharmacology
2009, International Journal for ParasitologyOxotremorine
2009, xPharm: The Comprehensive Pharmacology Reference