General paper1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [3H]norepinephrine release in rat hippocampal slices
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2007, Progress in Brain ResearchCitation Excerpt :Finally, cognitive enhancers significantly facilitate NE release in response to glutamate, even in the presence of the endogenous NMDA receptor antagonist, kynurenate (Pittaluga et al., 1997). This facilitation is suggested to be an important mediator of cognitive enhancement (Desai et al., 1995; Pittaluga et al., 2001). Conversely, NE enhances glutamate release in DG, an effect which depends on presynaptic β adrenoceptors (Lynch and Bliss, 1986).
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