Research paperBrain regional levels of adenosine and adenosine nucleotides in rats killed by high-energy focused microwave irradiation
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Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) for in situ analysis of endogenous small molecules in biological samples
2022, TrAC - Trends in Analytical ChemistryDevelopment of a quantification method for adenosine in tumors by LC-MS/MS with dansyl chloride derivatization
2019, Analytical BiochemistryCitation Excerpt :Previous publications discuss the quantification of adenosine in various matrices: plasma, cells from culture (and media), tissue perfusate, tissue sections, cerebrospinal fluid, urine; but the majority of these methods use a liquid chromatography system coupled with a UV or fluorescence detection [7,10–17], rather than LC-MS/MS [18–21]. Additionally, a select number of publications use a derivatization technique to improve selectivity and sensitivity joined with LC-UV or LC-fluorescence to improve the properties of adenosine in plasma, urine, and/or tissue perfusate [22–27]. None of the above methods quantify adenosine in tumor homogenate using LC-MS/MS, driving the need for a new method that may require additional sensitivity and specificity due to potentially wide variability between tumors in adenosine concentration.
Comparison of spontaneous and mechanically-stimulated adenosine release in mice
2019, Neurochemistry InternationalAdenosine has two faces: Regionally dichotomous adenosine tone in a model of epilepsy with comorbid sleep disorders
2018, Neurobiology of DiseaseBiotinidase knockout mice show cellular energy deficit and altered carbon metabolism gene expression similar to that of nutritional biotin deprivation: Clues for the pathogenesis in the human inherited disorder
2013, Molecular Genetics and MetabolismCitation Excerpt :The plate was finally placed in the auto-sampler for testing. ATP, ADP and AMP concentrations were determined by HPLC according to the method of Delaney and Geiger [9]. Mice were sacrificed by concussion.
Localisation of adenine nucleotides in heat-stabilised mouse brains using ion mobility enabled MALDI imaging
2013, International Journal of Mass Spectrometry