ArticleInteraction of ovine pituitary adenylate cyclase-activating peptide (PACAP-38) with rat lung membranes
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Cited by (10)
Modulatory role of PACAP and VIP on HIFs expression in lung adenocarcinoma
2021, PeptidesCitation Excerpt :PACAP binds the PAC1 receptor with higher affinity than VIP, whereas VPAC1/VIPAC2 receptors are similarly activated by both peptides [28]. These receptors are expressed in acini and submucosal glands of the trachea, in the epithelium of large bronchi and in small terminal bronchioles [29–34]. The expression of these peptides has also been detected in lung cancer where they exert contradictory roles: PACAP stimulates tumor cell growth whereas VIP acts differently depending on tissue phenotype [35,36].
Pituitary adenylate cyclase-activating polypeptide and its receptors: 20 Years after the discovery
2009, Pharmacological Reviews
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