Haptoglobin phenotype as a predictor of restenosis after percutaneous transluminal coronary angioplasty☆
Section snippets
Acknowledgements
We authors are grateful for the cooperation of the Rambam Coronary Catheterization Laboratory and Cardiology Department.
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Cited by (48)
Haptoglobin Genotype as a Prognostic Factor for Adverse Events in Coronary Artery Bypass Surgery in Diabetic Patients
2019, Heart Lung and CirculationHaptoglobin 2 allele associates with unstable carotid plaque and major cardiovascular events
2013, AtherosclerosisCitation Excerpt :If it will turn out that different Hp genotypes do indeed associate with distinct stroke subtypes, ultimately the determination of Hp genotypes might assist in stroke risk stratification and individualized pharmacogenomics. Hp2-2 genotype has previously been associated with the severity of myocardial infarction [22] and vascular complications in diabetics, including retinopathy, nephropathy, cardiovascular morbidity and restenosis after coronary intervention [14–18]. However, hp2 allele has not previously been associated with cardiovascular morbidity in the general population.
Haptoglobin genotype and its role in determining heme-iron mediated vascular disease
2012, Pharmacological ResearchHaptoglobin phenotypes and plasma haptoglobin levels in patients with abdominal aortic aneurysm
2011, Journal of Vascular SurgeryHaptoglobin gene polymorphism in type 2 diabetic patients with and without nephropathy: An Egyptian study
2007, European Journal of Internal MedicineCitation Excerpt :The increased antioxidant function of Hp 1-1 is thought to confer protection from angiopathies; however, Hp 2-2 is believed to be a major risk factor in several oxidative stress-related disease states [9]. This has been reported for coronary [10] and peripheral [11] atherosclerotic lesions, cardiac transplant vasculopathy [12], mortality in coronary heart disease [13], restenosis after coronary angioplasty [14]or stenting [15], and cardiovascular disease in diabetic individuals [16]. Also, the Hp phenotype is an apparent risk factor for the development of gestational diabetes mellitus [17].
The Pathophysiology and Burden of Restenosis
2007, American Journal of Cardiology
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This study was supported by grants from the Israel Cancer Association, Givatayim, Israel; Israel Cancer Research Fund, New York, New York; Israel Science Foundation, Jerusalem, Israel; Rappaport Fund for Research, Haifa, Israel; and the National Institutes of Health (NIHR01), Bethesda, Maryland.