Short communicationOpioid receptor gene: cytokine response element and the effect of cytokines
Section snippets
Acknowledgements
This research was supported by NIH research grants DA-00546, DA-01583, DA-05695, KO5-DA-70554, and A&F Stark fund of the Minnesota Medical Foundation. The authors would like to thank Dr. Sabita Roy for her invaluable discussions and kindness in providing IL-1β for this work.
References (21)
- et al.
Effect of interleukin-1 on the augmentation of human immunodeficiency virus gene expression
Biochem. Biophys. Res. Commun.
(1989) - et al.
The interleukin-1 beta-mediated regulation of proenkephalin and opioid receptor messenger RNA in primary astrocyte-enriched cultures
Neuroscience
(1997) - et al.
Differential expression of cytokine genes in HIV-1 tat transfected T and B cell lines
Biochem. Biophys. Res. Commun.
(1995) - et al.
Reversible G1 arrest induced by dimethyl sulfoxide in human lymphoid cell lines: dimethyl sulfoxide inhibits IL-6-induced differentiation of SKW6-CL4 into IgM-secreting plasma cells
Exp. Cell Res.
(1996) - et al.
Regulation of expression of the interleukin 6 gene: structure and function of the transcription factor NF-IL6
Ciba Foundation Symposium
(1992) - et al.
Interleukin 1 and interleukin 2 enhance proopiomelanocortin gene expression in pituitary cells
J. Immunol.
(1987) - et al.
Regulation of mu opioid receptor mRNA levels by activation of protein kinase C in human SH-SY5Y neuroblastoma cells
Anesthesiology
(1997) - et al.
Interleukin-1 induces the expression of μ-opioid receptor in endothelial cells
Immunopharmacology
(1998) - et al.
Induction of rat acute-phase proteins by interleukin 6 in vivo
Eur. J. Immunol.
(1998) - et al.
Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region
Mol. Cell. Biol.
(1994)
Cited by (13)
The paradoxical role of methionine enkephalin in tumor responses
2020, European Journal of PharmacologyCitation Excerpt :However, in some conditions, cytokines and opioid receptors may appear irrelevant. Further experiments revealed that there was no elevated opioid receptor expression in human myeloma cell line U266 and macrophage RAW264.7 stimulated with IL-1 or IL-6 (Im et al., 1999). Although these cells are not tumor cells, it can be proven indirectly that MENK positively correlates with pro-inflammatory cytokines.
Basic fibroblast growth factor activates the MAPK and NFκB pathways that converge on Elk-1 to control production of matrix metalloproteinase-13 by human adult articular chondrocytes
2007, Journal of Biological ChemistryCitation Excerpt :Human MMP-13 promoter construct and plasmid expression vector containing siRNA targeting Akt (Mu6pro-Akt1/2) and control siRNA plasmid construct (Mu6pro) were previously described (27, 29, 30). The p3xNFκBLuc plasmid construct, containing three copies of tandemly repeated NFκB response element sequences (5′-TTGGGCACTCCCTG-3′) of MMP-13 promoter region was achieved by placing the NFκB response elements of MMP-13 promoter region upstream of an SV40 promoter at the SacI site of the pGL3-promoter vector, which contains a luciferase reporter gene system (Promega) as described previously (31). Transient Transfection by Nucleofection (Electroporation)—Nucleofection methods were optimized for use with human articular chondrocytes by minor modifications of the instructions for the Nucleofector™ kit (Amaxa Biosystems) that have been described previously (18, 32).
The hypothalamus-pituitary-adrenal axis and opioid peptides
2003, NeuroImmune BiologyRegulation of opioid receptor expression
2002, Current Opinion in Pharmacology