Gender differences in cocaine dependent patients: a 6 month follow-up study
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Epidemiology of hospitalizations with cocaine use disorder: A 17-year U.S. national study
2021, Journal of Psychiatric ResearchGender differences in clinical outcomes for cocaine dependence: Randomized clinical trials of behavioral therapy and disulfiram
2014, Drug and Alcohol DependenceCitation Excerpt :An RCT (350M, 104F, 5 sites) comparing manual-guided psychotherapies (individual or group drug counseling, cognitive therapy, supportive expressive therapy) found no gender or gender-by-treatment effects on cocaine use outcomes, but men transitioned between use and abstinence states (or vice versa) more frequently (Gallop et al., 2007). Following inpatient treatment for cocaine use wherein within-treatment abstinence was ensured (64M, 37F), women were less likely than men to relapse to cocaine by 6-month follow-up (Weiss et al., 1997). However survey data from individuals who had undergone standard inpatient or outpatient treatment (i.e., not an RCT) (65M, 29F) found no gender differences in cocaine use outcomes at one year follow-up (McCance-Katz et al., 1999).
Reduced striatal volume in cocaine-dependent patients
2011, NeuroImageTestosterone is essential for cocaine sensitization in male rats
2011, Physiology and BehaviorCitation Excerpt :In other areas of study, the differences between sexes are more consistent, such as the increased reactivity of the hypothalamic-pituitary-adrenal axis to cocaine in females [14,16]. Gender differences have also been reported in the rate of developing dependence once exposed to cocaine [17,18], as well in the response to treatment [17,19,20]. These gender differences appear to be independent of drug pharmacokinetics [10–12].