Toll-like receptor 2 antagonists. Part 1: Preliminary SAR investigation of novel synthetic phospholipids
Graphical abstract
Phospholipid compound 1 was discovered as a novel antagonist of toll-like receptor 2 signaling. Synthesis and biological properties are described for 1 and eight related analogues.
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Acknowledgments
We thank Donna Young, Minglun Wang, Kara Loiacono, and Melinda Genest for developing and running the biological assays.
References and notes (14)
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