Current Biology
Volume 15, Issue 2, 26 January 2005, Pages R64-R67
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β-Catenin: A Pivot between Cell Adhesion and Wnt Signalling

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Abstract

Mutual adhesion of animal cells is intimately linked to Wnt signaling through a shared component: β-catenin, or Armadillo in Drosophila. Recent work indicates how β-catenin shifts from cell adhesion to Wnt signaling, a switch associated with epithelial–mesenchymal transitions and cancer.

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