Neuron
Volume 66, Issue 6, 24 June 2010, Pages 871-883
ArticleAn Epilepsy/Dyskinesia-Associated Mutation Enhances BK Channel Activation by Potentiating Ca2+ Sensing
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Highlights
► The two Ca2+-activation pathways in BK channels are dissected ► The AC region is identified as a structural component of one of the pathways ► Protein dynamics plays an important role in the AC region pathway ► The disease-associated mutation alters channel dynamics to enhance Ca2+ sensing
MOLNEURO
PROTEINS
HUMDISEASE
Cited by (0)
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Present address: Department of Biomedical Engineering and Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA
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These authors contributed equally to this work
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