Abstract
Ionic currents from individual K+ channels in squid axon membrane have been recorded. At hyperpolarizing membrane voltages, unit events occur as widely spaced rectangular pulses with short interruptions. The frequency of occurrence of the units increases strongly when the membrane is depolarized.
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References
Hodgkin, A. L. & Huxley, A. F. J. Physiol., Lond. 117, 500–544 (1952).
Hille, B. in Membranes: Lipid Bilayers and Biological Membranes: Dynamic Properties Vol. 3 (ed. Eisenman, G., 255–323 (Dekker, New York, 1975).
Ritchie, J. M. & Rogart, R. B. Rev. Physiol. biochem. Pharmac. 79, 1–50 (1977).
Conti, F., De Felice, L. J. & Wanke, E. J. Physiol., Lond. 248, 45–82 (1975).
Begenisich, T. & Stevens, C. F. Biophys. J. 15, 843–846 (1975).
Conti, F., Hille, B., Neumcke, B., Nonner, W. & Staempfli, R. J. Physiol., Lond. 262, 699–727 (1976).
Sigworth, F. J. Nature 270, 265–267 (1977).
Neher, E., Sakmann, B. & Steinbach, J. H. Pflügers Arch. ges. Physiol. 375, 219–228 (1978).
Tasaki, I., Watanabe, A. & Takenaka, T. Proc. natn. Acad. Sci. U.S.A. 48, 117–1184 (1962).
Armstrong, C. M., Bezanilla, F. & Rojas, E. J. gen. Physiol. 62, 375–391 (1973).
Chandler, W. K., Hodgkin, A. L. & Meves, H. J. Physiol., Lond. 180, 821–836 (1965).
Ehrenstein, G. & Gilbert, D. L. Biophys. J. 6, 553–566 (1966).
Neher, E. & Steinbach, J. H. J. Physiol., Lond. 227, 153–176 (1978).
Bezanilla, F. & Armstrong, C. M. J. gen. Physiol. 60, 558–608 (1972).
Keynes, R. D. & Lewis, P. R. J. Physiol., Lond. 114, 151–182 (1951).
Stuehmer, W. & Conti, F., in preparation
Colquhoun, D. & Hawkes, A. G. Proc. R. Soc. B199, 231–262 (1977).
Armstrong, C. M. J. gen. Physiol. 58, 413–437 (1971).
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Conti, F., Neher, E. Single channel recordings of K+ currents in squid axons. Nature 285, 140–143 (1980). https://doi.org/10.1038/285140a0
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DOI: https://doi.org/10.1038/285140a0
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