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A New Anti-oestrogenic Agent in Late Breast Cancer: An Early Clinical Appraisal of ICI46474

British Journal of Cancer volume 25, pages 270–275 (1971)Cite this article

Abstract

An introductory clinical trial of the anti-oestrogenic agent IC146474 in late or recurrent carcinoma of the breast is described.

Forty-six patients have been treated, of whom 10 have shown a good response. This is of the same order as that seen with oestrogens and androgens.

The particular advantage of this drug is the low incidence of troublesome side effects.

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Authors
  1. M P Cole
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  2. C T A Jones
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  3. I D H Todd
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Cole, M., Jones, C. & Todd, I. A New Anti-oestrogenic Agent in Late Breast Cancer: An Early Clinical Appraisal of ICI46474. Br J Cancer 25, 270–275 (1971). https://doi.org/10.1038/bjc.1971.33

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  • DOI: https://doi.org/10.1038/bjc.1971.33

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