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Successful management of adult respiratory distress syndrome (ARDS) after high-dose chemotherapy and peripheral blood progenitor cell rescue by non-invasive ventilatory support

Bone Marrow Transplantation volume 21, pages 1067–1069 (1998)Cite this article

Abstract

A 34-year-old man suffering from Hodgkin’s disease underwent high-dose chemotherapy (CBV) followed by transplantation of autologous peripheral blood stem cells. On day +6 after peripheral blood stem cell transplant (PBSCT) bacterial pneumonia developed. Along with rapid engraftment during stimulation with G-CSF adult respiratory distress syndrome (ARDS) developed within 4 days. High-flow CPAP (continuous positive airway pressure) ventilation via a sealed face-mask was initiated. The patient tolerated the sealed face-mask very well, and CPAP was continuously administered for 4 days, thus avoiding intubation. High-flow CPAP may offer a therapeutic alternative in selected patients with respiratory compromise after PBSCT.

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Authors and Affiliations

  1. Department of Internal Medicine I, Bone Marrow Transplantation Unit, University of Vienna, Austria

    W Rabitsch, SA Brugger, E Reiter, F Keil, HT Greinix & P Kalhs

  2. Department of Internal Medicine I, Intensive Care Unit, University of Vienna, Austria

    T Staudinger

  3. Department of Radiology, University of Vienna, Austria

    C Herold

  4. Department of Internal Medicine I, Hematology Unit, University of Vienna, Austria

    K Lechner

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  1. W Rabitsch
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  2. T Staudinger
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  3. SA Brugger
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  4. E Reiter
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  5. F Keil
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  6. C Herold
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  7. K Lechner
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  8. HT Greinix
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  9. P Kalhs
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Rabitsch, W., Staudinger, T., Brugger, S. et al. Successful management of adult respiratory distress syndrome (ARDS) after high-dose chemotherapy and peripheral blood progenitor cell rescue by non-invasive ventilatory support. Bone Marrow Transplant 21, 1067–1069 (1998). https://doi.org/10.1038/sj.bmt.1701215

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  • DOI: https://doi.org/10.1038/sj.bmt.1701215

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