Issue 12, 1996
From the journal:

Journal of the Chemical Society, Perkin Transactions 1

New anthracycline disaccharides. Synthesis of L-daunosaminyl-α(1 →4)-2-deoxy-L-rhamnosyl and of L-daunosaminyl-α(1 →4)-2-deoxy-L-fucosyl daunorubicin analogues

Fabio Animati,   Federico Arcamone,   Marco Berettoni,   Amalia Cipollone,   Maurizio Franciotti  and  Paolo Lombardi  

Abstract

The synthesis of the new disaccharide anthracyclines 20, 21, 24 and 25, where the daunosamine moiety is separated from the aglycone by either a rhamnose or a fucose residue, performed following a convergent procedure, gives insight into the configurational requirement of the first sugar residue and opens the way to a new class of antitumour anthracyclines.

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Article information

DOI
https://doi.org/10.1039/P19960001327
Article type
Paper

J. Chem. Soc., Perkin Trans. 1, 1996, 1327-1329

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New anthracycline disaccharides. Synthesis of L-daunosaminyl-α(1 →4)-2-deoxy-L-rhamnosyl and of L-daunosaminyl-α(1 →4)-2-deoxy-L-fucosyl daunorubicin analogues

F. Animati, F. Arcamone, M. Berettoni, A. Cipollone, M. Franciotti and P. Lombardi, J. Chem. Soc., Perkin Trans. 1, 1996, 1327 DOI: 10.1039/P19960001327

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