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Mutations in human gonadotropin and gonadotropin-receptor genes

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Abstract

This short review provides an update on the new information that has become available in the recent years about mutations and polymorphisms in the genes for gonadotropins and their receptors. Combining the types and locations of the mutations, their phenotypic effects, and the recently emerged information about the crystal structure of these molecules is providing us with increasingly detailed picture about the structurefunction relationships of gonadotropin action.

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Authors and Affiliations

  1. Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, Du Cane Road, W12 0NN, London, U.K.

    I. T. Huhtaniemi MD, PhD

  2. Department of Internal Medicine, Erasmus MC, PO Box 1738, 3000 DR, Rotterdam, The Netherlands

    A. P. N. Themmen

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  1. I. T. Huhtaniemi MD, PhD
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Huhtaniemi, I.T., Themmen, A.P.N. Mutations in human gonadotropin and gonadotropin-receptor genes. Endocr 26, 207–217 (2005). https://doi.org/10.1385/ENDO:26:3:207

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