Advances in our understanding of aging: role of the renin-angiotensin system

Curr Opin Pharmacol. 2002 Apr;2(2):189-94. doi: 10.1016/s1471-4892(02)00139-x.

Abstract

Knowledge about the pathophysiological role of the renin-angiotensin system is constantly improving and its relationship with mechanisms of oxidative stress suggests its possible involvement with the deleterious effects of aging. Recent data opens a new field of investigation in this area.

Publication types

  • Review

MeSH terms

  • Aging / drug effects
  • Aging / physiology*
  • Angiotensin Receptor Antagonists
  • Angiotensin-Converting Enzyme Inhibitors / pharmacology
  • Angiotensin-Converting Enzyme Inhibitors / therapeutic use
  • Animals
  • Cognition / drug effects
  • Cognition / physiology
  • Humans
  • Kidney / drug effects
  • Kidney / physiology
  • Receptors, Angiotensin / physiology
  • Renin-Angiotensin System / drug effects
  • Renin-Angiotensin System / physiology*

Substances

  • Angiotensin Receptor Antagonists
  • Angiotensin-Converting Enzyme Inhibitors
  • Receptors, Angiotensin