On long-term depression induced by activation of G-protein coupled receptors

Zafar I Bashir

doi:10.1016/s0168-0102(03)00002-6

On long-term depression induced by activation of G-protein coupled receptors

Neurosci Res. 2003 Apr;45(4):363-7. doi: 10.1016/s0168-0102(03)00002-6.

Author

Zafar I Bashir¹

Affiliation

¹ MRC Centre for Synaptic Plasticity, Department of Anatomy, University of Bristol, Bristol BS8 1TD, UK. z.i.bashir@bris.ac.uk

PMID: 12657448
DOI: 10.1016/s0168-0102(03)00002-6

Abstract

In this mini-review I consider the mechanisms by which activation of glutamate and acetylcholine metabotropic receptors can result in the induction of long-term depression. Two regions of the CNS will receive particular attention; the CA1 region of hippocampus and the perirhinal cortex.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Brain / physiology
Long-Term Synaptic Depression / physiology*
Neuronal Plasticity / physiology
Receptors, Cholinergic / metabolism*
Receptors, Metabotropic Glutamate / physiology*
Signal Transduction / physiology

Substances

Receptors, Cholinergic
Receptors, Metabotropic Glutamate