Schizophrenia drug gets negative results for negative symptoms

Nat Rev Drug Discov. 2014 Apr;13(4):244-5. doi: 10.1038/nrd4294.
No abstract available

MeSH terms

  • Antipsychotic Agents / pharmacology
  • Antipsychotic Agents / therapeutic use*
  • Clinical Trials, Phase II as Topic
  • Glycine Plasma Membrane Transport Proteins / antagonists & inhibitors
  • Humans
  • Piperazines / pharmacology
  • Piperazines / therapeutic use*
  • Schizophrenia / drug therapy*
  • Schizophrenia / physiopathology
  • Schizophrenic Psychology
  • Sulfones / pharmacology
  • Sulfones / therapeutic use*
  • Treatment Outcome

Substances

  • (4-(3-fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl)(5-methanesulfonyl-2-(2,2,2-trifluoro-1-methylethoxy)phenyl)methanone
  • Antipsychotic Agents
  • Glycine Plasma Membrane Transport Proteins
  • Piperazines
  • SLC6A9 protein, human
  • Sulfones