Abstract
Cerebral capillary endothelium forms a barrier limiting and controlling the movement of ions and solutes between blood and brain. Recent anatomical, physiological and biochemical studies have suggested the possibility that capillary function may be directly controlled by neuronal structures. Alterations in neuronal systems involved in the regulation of microcirculation may account for microvascular dysfunctions which occur in different pathologic conditions.
MeSH terms
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Acetylcholine / physiology
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Aging
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Animals
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Biological Transport, Active
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Blood-Brain Barrier
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Brain / blood supply*
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Brain / growth & development
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Capillaries / innervation
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Capillaries / ultrastructure
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Capillary Permeability
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Cerebrovascular Circulation
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Cholecystokinin / physiology
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Diabetes Mellitus / physiopathology
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Dopamine / physiology
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Endothelium / physiology
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Histamine / physiology
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Hypertension / physiopathology
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Hypoxia, Brain / physiopathology
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Locus Coeruleus / physiology
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Microcirculation / innervation
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Microcirculation / ultrastructure
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Neural Pathways / physiology
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Neurons / physiology*
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Norepinephrine / physiology
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Receptors, Neurotransmitter / physiology
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Serotonin / physiology
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Substance P / physiology
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Vasoactive Intestinal Peptide / physiology
Substances
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Receptors, Neurotransmitter
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Serotonin
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Substance P
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Vasoactive Intestinal Peptide
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Histamine
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Cholecystokinin
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Acetylcholine
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Dopamine
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Norepinephrine