Pure red cell aplasia associated with administration of sustained-release procainamide

Arch Intern Med. 1987 Jun;147(6):1179-80.

Abstract

Pure red cell aplasia developed in a patient with small-cell lung cancer who was also taking sustained-release procainamide. Shortly after discontinuation of the procainamide preparation, a reticulocytosis and increasing hemoglobin level were observed.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Anemia, Aplastic / chemically induced*
  • Carcinoma, Small Cell / drug therapy
  • Delayed-Action Preparations
  • Drug Therapy, Combination
  • Humans
  • Lung Neoplasms / drug therapy
  • Male
  • Myocardial Infarction / drug therapy
  • Procainamide / administration & dosage
  • Procainamide / adverse effects*

Substances

  • Delayed-Action Preparations
  • Procainamide