Filppula AM[au] - Search Results

Year	Number of Results
2011	1
2012	2
2013	2
2014	2
2016	2
2017	2
2018	3
2019	3
2021	4
2022	2
2023	4
2024	3

1

Role of Cytochrome P450 2C8 in Drug Metabolism and Interactions.

Backman JT, Filppula AM, Niemi M, Neuvonen PJ. Backman JT, et al. Among authors: filppula am. Pharmacol Rev. 2016 Jan;68(1):168-241. doi: 10.1124/pr.115.011411. Pharmacol Rev. 2016. PMID: 26721703 Review.

2

Rhabdomyolysis during concomitant ticagrelor and rosuvastatin: A breast cancer resistance protein-mediated drug interaction?

Lehtisalo M, Kiander W, Filppula AM, Deng F, Kidron H, Korhonen M, Sinkko J, Koivula K, Niemi M. Lehtisalo M, et al. Among authors: filppula am. Br J Clin Pharmacol. 2023 Jul;89(7):2309-2315. doi: 10.1111/bcp.15684. Epub 2023 Feb 20. Br J Clin Pharmacol. 2023. PMID: 36740817 Review.

3

Real-world pharmacogenetics of statin intolerance: effects of SLCO1B1, ABCG2 , and CYP2C9 variants.

Lönnberg KI, Tornio A, Hirvensalo P, Keskitalo J, Mustaniemi AL, Kiiski JI, Filppula AM, Niemi M. Lönnberg KI, et al. Among authors: filppula am. Pharmacogenet Genomics. 2023 Sep 1;33(7):153-160. doi: 10.1097/FPC.0000000000000504. Epub 2023 Jul 23. Pharmacogenet Genomics. 2023. PMID: 37490620 Free PMC article.

4

Translational aspects of cytochrome P450-mediated drug-drug interactions: A case study with clopidogrel.

Tornio A, Filppula AM, Backman JT. Tornio A, et al. Among authors: filppula am. Basic Clin Pharmacol Toxicol. 2022 Jan;130 Suppl 1:48-59. doi: 10.1111/bcpt.13647. Epub 2021 Sep 25. Basic Clin Pharmacol Toxicol. 2022. PMID: 34410044 Free article. Review.

5

Clinical Studies on Drug-Drug Interactions Involving Metabolism and Transport: Methodology, Pitfalls, and Interpretation.

Tornio A, Filppula AM, Niemi M, Backman JT. Tornio A, et al. Among authors: filppula am. Clin Pharmacol Ther. 2019 Jun;105(6):1345-1361. doi: 10.1002/cpt.1435. Epub 2019 Apr 20. Clin Pharmacol Ther. 2019. PMID: 30916389 Free PMC article. Review.

6

Ticagrelor Increases Exposure to the Breast Cancer Resistance Protein Substrate Rosuvastatin.

Lehtisalo M, Tarkiainen EK, Neuvonen M, Holmberg M, Kiiski JI, Lapatto-Reiniluoto O, Filppula AM, Kurkela M, Backman JT, Niemi M. Lehtisalo M, et al. Among authors: filppula am. Clin Pharmacol Ther. 2024 Jan;115(1):71-79. doi: 10.1002/cpt.3067. Epub 2023 Oct 20. Clin Pharmacol Ther. 2024. PMID: 37786998 Clinical Trial.

7

Comparative Hepatic and Intestinal Efflux Transport of Statins.

Deng F, Tuomi SK, Neuvonen M, Hirvensalo P, Kulju S, Wenzel C, Oswald S, Filppula AM, Niemi M. Deng F, et al. Among authors: filppula am. Drug Metab Dispos. 2021 Sep;49(9):750-759. doi: 10.1124/dmd.121.000430. Epub 2021 Jun 23. Drug Metab Dispos. 2021. PMID: 34162690

8

Comparative Hepatic and Intestinal Metabolism and Pharmacodynamics of Statins.

Filppula AM, Hirvensalo P, Parviainen H, Ivaska VE, Lönnberg KI, Deng F, Viinamäki J, Kurkela M, Neuvonen M, Niemi M. Filppula AM, et al. Drug Metab Dispos. 2021 Aug;49(8):658-667. doi: 10.1124/dmd.121.000406. Epub 2021 May 27. Drug Metab Dispos. 2021. PMID: 34045219

9

Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations.

Filppula AM, Parvizi R, Mateus A, Baranczewski P, Artursson P. Filppula AM, et al. Sci Rep. 2019 Apr 10;9(1):5850. doi: 10.1038/s41598-019-42051-x. Sci Rep. 2019. PMID: 30971754 Free PMC article.

10

Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro.

Paludetto MN, Kurkela M, Kahma H, Backman JT, Niemi M, Filppula AM. Paludetto MN, et al. Among authors: filppula am. Drug Metab Dispos. 2023 Mar;51(3):293-305. doi: 10.1124/dmd.122.001018. Epub 2022 Nov 29. Drug Metab Dispos. 2023. PMID: 36446607

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