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Did you mean number s[au] (173 results)?
Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment.
Fanning S, Haque A, Imberdis T, Baru V, Barrasa MI, Nuber S, Termine D, Ramalingam N, Ho GPH, Noble T, Sandoe J, Lou Y, Landgraf D, Freyzon Y, Newby G, Soldner F, Terry-Kantor E, Kim TE, Hofbauer HF, Becuwe M, Jaenisch R, Pincus D, Clish CB, Walther TC, Farese RV Jr, Srinivasan S, Welte MA, Kohlwein SD, Dettmer U, Lindquist S, Selkoe D. Fanning S, et al. Among authors: nuber s. Mol Cell. 2019 Mar 7;73(5):1001-1014.e8. doi: 10.1016/j.molcel.2018.11.028. Epub 2018 Dec 4. Mol Cell. 2019. PMID: 30527540 Free PMC article.
Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activity.
Ramalingam N, Jin SX, Moors TE, Fonseca-Ornelas L, Shimanaka K, Lei S, Cam HP, Watson AH, Brontesi L, Ding L, Hacibaloglu DY, Jiang H, Choi SJ, Kanter E, Liu L, Bartels T, Nuber S, Sulzer D, Mosharov EV, Chen WV, Li S, Selkoe DJ, Dettmer U. Ramalingam N, et al. Among authors: nuber s. NPJ Parkinsons Dis. 2023 Jan 16;9(1):4. doi: 10.1038/s41531-023-00444-w. NPJ Parkinsons Dis. 2023. PMID: 36646701 Free PMC article.
A Brain-Penetrant Stearoyl-CoA Desaturase Inhibitor Reverses α-Synuclein Toxicity.
Nuber S, Chung CY, Tardiff DF, Bechade PA, McCaffery TD, Shimanaka K, Choi J, Chang B, Raja W, Neves E, Burke C, Jiang X, Xu P, Khurana V, Dettmer U, Fanning S, Rhodes KJ, Selkoe DJ, Scannevin RH. Nuber S, et al. Neurotherapeutics. 2022 Apr;19(3):1018-1036. doi: 10.1007/s13311-022-01199-7. Epub 2022 Apr 20. Neurotherapeutics. 2022. PMID: 35445353 Free PMC article.
Wild-type GBA1 increases the α-synuclein tetramer-monomer ratio, reduces lipid-rich aggregates, and attenuates motor and cognitive deficits in mice.
Glajch KE, Moors TE, Chen Y, Bechade PA, Nam AY, Rajsombath MM, McCaffery TD, Dettmer U, Weihofen A, Hirst WD, Selkoe DJ, Nuber S. Glajch KE, et al. Among authors: nuber s. Proc Natl Acad Sci U S A. 2021 Aug 3;118(31):e2103425118. doi: 10.1073/pnas.2103425118. Proc Natl Acad Sci U S A. 2021. PMID: 34326260 Free PMC article.
Caspase-1 clipping causes complications for α-synuclein.
Nuber S, Selkoe DJ. Nuber S, et al. Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):9958-60. doi: 10.1073/pnas.1610993113. Epub 2016 Aug 22. Proc Natl Acad Sci U S A. 2016. PMID: 27551083 Free PMC article. No abstract available.
59 results