User profiles for Alex Nivorozhkin
Alex NivorozhkinNeo-Advent Technologies LLC Verified email at neo-adventtec.com Cited by 3916 |
Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol
The prototypical xanthine oxidase (XO) inhibitor allopurinol, has been the cornerstone of the
clinical management of gout and conditions associated with hyperuricemia for several …
clinical management of gout and conditions associated with hyperuricemia for several …
Ligand environment and the structure of Schiff base adducts and tetracoordinated metal-chelates
AD Garnovskii, AL Nivorozhkin, VI Minkin - Coordination chemistry reviews, 1993 - Elsevier
Since the seminal works by Ettling, Schiff and Pfeiffer (see ref. 1 and the references cited
therein) metal-chelate Schiff base complexes have continued to play the role of one of the most …
therein) metal-chelate Schiff base complexes have continued to play the role of one of the most …
Enzyme-Activated Gd3+ Magnetic Resonance Imaging Contrast Agents with a Prominent Receptor-Induced Magnetization Enhancement.
AL Nivorozhkin, AF Kolodziej, P Caravan… - … (International ed. in …, 2001 - europepmc.org
Clinically relevant relaxivity enhancement of a magnetic resonance imaging (MRI) contrast
agent has been achieved by using prodrug Gd 3+ complexes (see picture, DTPA= …
agent has been achieved by using prodrug Gd 3+ complexes (see picture, DTPA= …
Critical process parameters in manufacturing of liposomal formulations of amphotericin B
Identifying the critical process parameters (CPPs) of a complex drug product manufacture
and the associated impact on critical quality attributes (CQAs) is essential to the development …
and the associated impact on critical quality attributes (CQAs) is essential to the development …
Facile and Convenient Syntheses of 6,11-Dihydro-5H-indeno[1,2-c]isoquinolin- 5-ones and 6,11-Dihydro-5H-indolo[3,2-c]isoquinolin-5-one
…, G Southan, W Williams, A Roy, A Nivorozhkin… - Organic …, 2005 - ACS Publications
The synthesis of 6,11-dihydro-5H-indeno[1,2-c]isoquinolin-5-ones from the base-promoted
condensation reaction of homophthalic anhydride and 2-(bromomethyl)-benzonitrile and a …
condensation reaction of homophthalic anhydride and 2-(bromomethyl)-benzonitrile and a …
Synthesis and Structure–Activity Relationships of 2, 5-Dimethoxy-4-Substituted Phenethylamines and the Discovery of CYB210010: A Potent, Orally Bioavailable and …
…, E Stang, MG Palfreyman, A Nivorozhkin - Journal of Medicinal …, 2024 - ACS Publications
Structure–activity studies of 4-substituted-2,5-dimethoxyphenethylamines led to the discovery
of 2,5-dimethoxy-4-thiotrifluoromethylphenethylamines, including CYB210010, a potent …
of 2,5-dimethoxy-4-thiotrifluoromethylphenethylamines, including CYB210010, a potent …
Optimization of the manufacturing process of a complex amphotericin B liposomal formulation using quality by design approach
In this work, the manufacturing process of a complex liposomal amphotericin B (AmB)
product was optimized using quality by design (QbD) approach. A comprehensive QbD-based …
product was optimized using quality by design (QbD) approach. A comprehensive QbD-based …
Structure and Electrochemical Studies of [(trispicMeen)ClFeIIIOFeIIICl(trispicMeen)]2+. Spectroscopic Characterization of the Mixed-Valence FeIIIOFeII Form …
AL Nivorozhkin, E Anxolabehere-Mallart… - Inorganic …, 1997 - ACS Publications
The dinuclear species [(trispicMeen)ClFe III OFe III Cl(trispicMeen)]Cl(OH)(H 2 O) 7 (1) (trispicMeen
= N,N,N‘-tris(2-pyridylmethyl)-N‘-methylethane-1,2-diamine) was synthesized. It …
= N,N,N‘-tris(2-pyridylmethyl)-N‘-methylethane-1,2-diamine) was synthesized. It …
Probing pharmaceutical powder blending uniformity with electrostatic charge measurements
T Hao, J Tukianen, A Nivorozhkin, N Landrau - Powder technology, 2013 - Elsevier
The tribo-electrification of the powder particles is ubiquitous in pharmaceutical powder
blending processes. It usually carries a negative connotation as particles may jam and stick …
blending processes. It usually carries a negative connotation as particles may jam and stick …
Metallocyclopeptide Complexes with MII(S·Cys)4 Chromophores
AL Nivorozhkin, BM Segal, KB Musgrave… - Inorganic …, 2000 - ACS Publications
The tetracysteinyl peptide cyclo[Lys 1,12 ](Gln-Cys-Gly-Val-Cys-Gly-Lys-Cys-Ile-Ala-Cys-Lys)
(⊂L(Cys·SH) 4 ) was synthesized by solid-phase methods using an Fmoc/t-Bu/allyl …
(⊂L(Cys·SH) 4 ) was synthesized by solid-phase methods using an Fmoc/t-Bu/allyl …