Aspects of 5-hydroxyindole metabolism have been studied in some groups of mentally
retarded children. Six of 23 children with the diagnosis of infantile autism had consistently …

Whole blood serotonin and tryptophan were measured in 87 normal subjects and in 40 autistic
subjects. Whole blood serotonin concentration (mean ± SE) were significantly higher in …

• A patient with a 62-year history of Gilles de la Tourette syndrome describes 35 years of self-observation
of the subjective events that precede, accompany, and follow the occurrence of …

• Mean whole blood serotonin (5-HT) levels were elevated in groups of autistic and severely
retarded children. Eight of 27 (30%) individual autistic children, 13 of 25 (52%) severely …

• Nine volunteer subjects were tested with intravenously administered cocaine hydrochloride
in doses ranging from 4 to 32 mg, as well as 10 mg of dextroamphetamine sulfate. …

The disease which thus evokes these new and wonderful talents and operations of the mind
may be compared to an earthquake which, by convulsing the upper strata of our globe, …

WHILE SCIENTISTS may debate the appropriate use of hallucinogens, history records our
unceasing urge to cope with dreary reality or dread with the aid of magic, drugs, drama, …

A dosage regimen of lysergic acid diethylamide (LSD) that reliably produces behavioral
tolerance in rats was evaluated for effects on neurotransmitter receptor binding in rat brain using …

Daily administration of D-lysergic acid diethylamide (LSD) was previously shown to decrease
serotonin 2 (5-HT 2 ) receptor binding in rat brain. Recently, 4-substituted derivatives of 1-(…

THE DISCOVERY that alterations in electroencephalographic (EEG) sleep patterns can be
quantified has provoked numerous studies of the relationship of changes in sleep-stage …