[PDF][PDF] Cell of origin of small cell lung cancer: inactivation of Trp53 and Rb1 in distinct cell types of adult mouse lung

KD Sutherland, N Proost, I Brouns, D Adriaensen… - Cancer cell, 2011 - cell.com
Small cell lung cancer (SCLC) is one of the most lethal human malignancies. To investigate
the cellular origin(s) of this cancer, we assessed the effect of Trp53 and Rb1 inactivation in …

Purinergic signaling in the airways

G Burnstock, I Brouns, D Adriaensen… - Pharmacological …, 2012 - ASPET
Evidence for a significant role and impact of purinergic signaling in normal and diseased
airways is now beyond dispute. The present review intends to provide the current state of …

Outer submucous plexus: an intrinsic nerve network involved in both secretory and motility processes in the intestine of large mammals and humans

…, J Hens, D Adriaensen - The Anatomical Record …, 2001 - Wiley Online Library
The architecture of the enteric nerve networks in the gastrointestinal tract appears to be more
complex in large mammals, including humans, than in small laboratory animals. At least …

Cytoskeletal rearrangements and cell extensions induced by the US3 kinase of an alphaherpesvirus are associated with enhanced spread

…, G Van Minnebruggen, D Adriaensen… - Proceedings of the …, 2005 - National Acad Sciences
The US3 protein is a viral kinase that is conserved among the Alphaherpesvirinae. Here, we
show that US3 of the swine alphaherpesvirus pseudorabies virus causes dramatic …

Structural organization and neuropeptide distribution in the mammalian enteric nervous system, with special attention to those components involved in mucosal …

JP Timmermans, D Adriaensen, W Cornelissen… - … and Physiology Part A …, 1997 - Elsevier
Gastrointestinal events such as peristalsis and secretion/absorption processes are influenced
by the enteric nervous system, which is capable of acting largely independently from other …

[PDF][PDF] The auxin-regulated CrRLK1L kinase ERULUS controls cell wall composition during root hair tip growth

…, R Swarup, WH De Vos, I Pintelon, D Adriaensen… - Current Biology, 2018 - cell.com
Root hairs facilitate a plant's ability to acquire soil anchorage and nutrients. Root hair growth
is regulated by the plant hormone auxin and dependent on localized synthesis, secretion, …

Functional morphology of pulmonary neuroepithelial bodies: extremely complex airway receptors

D Adriaensen, I Brouns… - … Record Part A …, 2003 - Wiley Online Library
Innervated groups of neuroendocrine cells, called neuroepithelial bodies (NEBs), are
diffusely spread in the epithelium of intrapulmonary airways in many species. Our present …

The role (s) of somatostatin, structurally related peptides and somatostatin receptors in the gastrointestinal tract: a review

D Adriaensen, L Van Nassauw, JP Timmermans - Regulatory peptides, 2009 - Elsevier
Extensive functional and morphological research has demonstrated the pivotal role of
somatostatin (SOM) in the regulation of a wide variety of gastrointestinal activities. In addition to its …

The bidirectional communication between neurons and mast cells within the gastrointestinal tract

L Van Nassauw, D Adriaensen… - Autonomic Neuroscience, 2007 - Elsevier
Normal or disordered behaviour of the gastrointestinal tract is determined by a complex
interplay between the epithelial barrier, immune cells, blood vessels, smooth muscle and …

Evidence for a role of neuroepithelial bodies as complex airway sensors: comparison with smooth muscle-associated airway receptors

D Adriaensen, I Brouns, I Pintelon… - Journal of Applied …, 2006 - journals.physiology.org
The epithelium of intrapulmonary airways in many species harbors diffusely spread
innervated groups of neuroendocrine cells, called neuroepithelial bodies (NEBs). Data on the …