International Union of Pharmacology. XXXV. The glucagon receptor family

KE Mayo, LJ Miller, D Bataille, S Dalle, B Göke… - Pharmacological …, 2003 - ASPET
Peptide hormones within the secretin-glucagon family are expressed in endocrine cells of
the pancreas and gastrointestinal epithelium and in specialized neurons in the brain, and …

The forgotten members of the glucagon family

D Bataille, S Dalle - Diabetes Research and Clinical Practice, 2014 - Elsevier
From proglucagon, at least six final biologically active peptides are produced by tissue-specific
post-translational processing. While glucagon and GLP-1 are the subject of permanent …

ERK1/2 control phosphorylation and protein level of cAMP-responsive element–binding protein: a key role in glucose-mediated pancreatic β-cell survival

S Costes, C Broca, G Bertrand, AD Lajoix, D Bataille… - …, 2006 - Am Diabetes Assoc
cAMP-responsive element–binding protein (CREB) is required for β-cell survival by regulating
expression of crucial genes such as bcl-2 and IRS-2. Using MIN6 cells and isolated rat …

Pro-protein convertases in intermediary metabolism: islet hormones, brain/gut hormones and integrated physiology

D Bataille - Journal of molecular medicine, 2007 - Springer
Many peptide hormones implicated in the regulation of intermediary metabolism arise from
larger precursors called prohormones. These precursors are cut into pieces by proprotein …

Extracellularly regulated kinases 1/2 (p44/42 mitogen-activated protein kinases) phosphorylate synapsin I and regulate insulin secretion in the MIN6 β-cell line and …

…, C Broca, S Costes, EH Hani, D Bataille… - …, 2005 - academic.oup.com
The p44/p42 MAPKs (ERK1/2) cascade regulates β-cell nuclear events, which modulates cell
differentiation and gene transcription, whereas its implication in processes occurring in the …

Labial salivary gland biopsy is a reliable test for the diagnosis of primary and secondary amyloidosis. A prospective clinical and immunohistologic study in 59 patients

…, RM Flipo, R Saïle, T Facon, D Bataille… - … : Official Journal of …, 1993 - Wiley Online Library
Objective. Reports of the detection of amyloidosis by labial salivary gland (LSG) biopsy have
been mostly anecdotal. The aim of this study was to assess the value of this method in the …

Effects of ectopic decorin in modulating intracranial glioma progression in vivo, in a rat syngeneic model

A Biglari, D Bataille, U Naumann, M Weller… - Cancer gene …, 2004 - nature.com
Given the failure of conventional treatments for glioblastoma, gene therapy has gained interest
considerable in recent years. Gliomas are associated with a state of immunosuppression, …

Human α-endosulfine, a possible regulator of sulfonylurea-sensitive KATP channel: Molecular cloning, expression and biological properties

…, A Le Cam, FM Ashcroft, D Bataille - Proceedings of the …, 1998 - National Acad Sciences
Sulfonylureas are a class of drugs commonly used in the management of non-insulin-dependent
diabetes mellitus. Their therapeutic action results primarily from their ability to inhibit …

[HTML][HTML] Glucagon promotes cAMP-response element-binding protein phosphorylation via activation of ERK1/2 in MIN6 cell line and isolated islets of Langerhans

…, C Broca, O Faruque, G Fontés, D Bataille - Journal of Biological …, 2004 - ASBMB
By using the MIN6 cell line and pancreatic islets, we show that in the presence of a low
glucose concentration, corresponding to physiological glucagon release from α cells, glucagon …

Endosulfine, an endogenous peptidic ligand for the sulfonylurea receptor: purification and partial characterization from ovine brain.

…, B Lupo, M Dufour, D Bataille - Proceedings of the …, 1992 - National Acad Sciences
Antidiabetic sulfonylureas act through receptors coupled to ATP-dependent potassium
channels. Using the binding of [3H]glibenclamide, a highly potent sulfonylurea, to rat brain …