Resistance to drug treatment is an important hurdle in the therapy of many brain disorders,
including brain cancer, epilepsy, schizophrenia, depression and infection of the brain with HIV…

The blood–brain barrier (BBB) serves as a protective mechanism for the brain by preventing
entry of potentially harmful substances from free access to the central nervous system (CNS)…

Dogs with spontaneous diseases can exhibit a striking similarity in etiology, clinical manifestation,
and disease course when compared to human patients. Therefore, dogs are intensely …

Epilepsy, one of the most common neurologic disorders, is a major public health issue. Despite
more than 20 approved antiepileptic drugs (AEDs), about 30% of patients are refractory …

Purpose: Weak direct currents induce lasting alterations of cortical excitability in animals
and humans, which are controlled by polarity, duration of stimulation, and current strength …

Purpose: Animal models in which seizures are elicited by chemical or electrical means are
commonly used for identification and preclinical testing of novel antiepileptic drugs (AEDs). …

Welches Analgetikum passt zu meinem Patienten? Mit welchen Nebenwirkungen muss ich
rechnen? Und in welchem Fall sollte ich von der Verwendung Abstand nehmen? Gründlich …

▪ Unterdrückung von angstassoziierten Verhaltensweisen (Trennung, Reise) bei Kleintieren
(Antidepressiva) Verschiedene generelle Gesichtspunkte müssen bei der Verabreichung …

The blood-brain barrier (BBB) contributes to brain homeostasis by protecting the brain from
potentially harmful endogenous and exogenous substances. BBB active drug efflux …

Epilepsy is a chronic neurologic disorder that affects over 70 million people worldwide. Despite
the availability of over 20 antiseizure drugs (ASDs) for symptomatic treatment of epileptic …