User profiles for Helen Cox
 | Helen CoxMedical Microbiology, University of CapeTown Verified email at uct.ac.za Cited by 14632 |
[HTML][HTML] Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB/RIF test for diagnosis of tuberculosis and multidrug resistance: a …
Background The Xpert MTB/RIF test (Cepheid, Sunnyvale, CA, USA) can detect tuberculosis
and its multidrug-resistant form with very high sensitivity and specificity in controlled studies, …
and its multidrug-resistant form with very high sensitivity and specificity in controlled studies, …
XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors
MC Michel, A Beck-Sickinger, H Cox, HN Doods… - Pharmacological …, 1998 - ASPET
Based on structural and evolutionary criteria, neuropeptide Y (NPY) b, peptide YY (PYY) and
pancreatic polypetide (PP) are closely related polypeptides (Larhammar, 1996a). They are …
pancreatic polypetide (PP) are closely related polypeptides (Larhammar, 1996a). They are …
[HTML][HTML] FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2
…, D Clements, P Humphreys, J Herriott, E Kijak, H Cox… - Nature, 2023 - nature.com
Preventing SARS-CoV-2 infection by modulating viral host receptors, such as angiotensin-converting
enzyme 2 (ACE2) 1 , could represent a new chemoprophylactic approach for …
enzyme 2 (ACE2) 1 , could represent a new chemoprophylactic approach for …
[HTML][HTML] Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients
…, M Burgos, R Centis, ED Chan, CY Chiang, H Cox… - 2012 - journals.plos.org
Background Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic,
expensive, and has generally poor outcomes. We undertook an individual patient data meta-…
expensive, and has generally poor outcomes. We undertook an individual patient data meta-…
[HTML][HTML] Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP …
…, JJ Clark, EA Clarke, S Cole, L Cooper, H Cox… - The Lancet …, 2021 - thelancet.com
Background Microbiological characterisation of co-infections and secondary infections in
patients with COVID-19 is lacking, and antimicrobial use is high. We aimed to describe …
patients with COVID-19 is lacking, and antimicrobial use is high. We aimed to describe …
[PDF][PDF] Clinical and molecular phenotype of Aicardi-Goutieres syndrome
…, HJ Christen, PC Corry, FM Cowan, H Cox… - The American Journal of …, 2007 - cell.com
Aicardi-Goutičres syndrome (AGS) is a genetic encephalopathy whose clinical features mimic
those of acquired in utero viral infection. AGS exhibits locus heterogeneity, with mutations …
those of acquired in utero viral infection. AGS exhibits locus heterogeneity, with mutations …
Evolutionary history and global spread of the Mycobacterium tuberculosis Beijing lineage
Mycobacterium tuberculosis strains of the Beijing lineage are globally distributed and are
associated with the massive spread of multidrug-resistant (MDR) tuberculosis in Eurasia. Here …
associated with the massive spread of multidrug-resistant (MDR) tuberculosis in Eurasia. Here …
Resistance to fluoroquinolones and second-line injectable drugs: impact on multidrug-resistant TB outcomes
A meta-analysis for response to treatment was undertaken using individual data of multidrug-resistant
tuberculosis (MDR-TB) (resistance to isoniazid and rifampicin) patients from 26 …
tuberculosis (MDR-TB) (resistance to isoniazid and rifampicin) patients from 26 …
Regional sympathetic nervous activity and oxygen consumption in obese normotensive human subjects
Background Disturbed sympathetic nervous function may be of importance in obesity;
sympathetic underactivity could contribute to deficient thermogenesis, positive energy balance, …
sympathetic underactivity could contribute to deficient thermogenesis, positive energy balance, …
Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing
…, F Bu'Lock, N Canham, IG Colgiu, C Cosgrove, H Cox… - Nature …, 2016 - nature.com
Congenital heart defects (CHDs) have a neonatal incidence of 0.8–1% (refs. 1 , 2 ). Despite
abundant examples of monogenic CHD in humans and mice, CHD has a low absolute …
abundant examples of monogenic CHD in humans and mice, CHD has a low absolute …