G protein-coupled receptors (GPCRs) are known to interact with several other classes of
integral membrane proteins that modulate their biology and pharmacology. However, the extent …

Pathogen-related signals induce a number of cytosolic pattern-recognition receptors (PRRs)
to form canonical inflammasomes, which activate pro-caspase-1 and trigger pyroptotic cell …

Receptor activity–modifying proteins (RAMPs) have been shown to modulate the functions
of several G protein–coupled receptors (GPCRs), but potential direct interactions among the …

Protein lysine fatty acylation is increasingly recognized as a prevalent and important protein
post-translation modification. Recently, it has been shown that K-Ras4a, R-Ras2, and Rac1 …

G protein–coupled receptors (GPCRs) control critical cellular signaling pathways. Therapeutic
agents including anti-GPCR antibodies (Abs) are being developed to modulate GPCR …

Cholestatic itch is a severe and debilitating symptom in liver diseases with limited treatment
options. The class A G protein-coupled receptor (GPCR) Mas-related GPCR subtype X4 (…

G protein-coupled receptors (GPCRs) are known to interact with several other classes of
integral membrane proteins that modulate their biology and pharmacology. However, the extent …

Receptor activity-modifying proteins (RAMPs) can form complexes with G protein-coupled
receptors (GPCRs) and regulate their cellular trafficking and pharmacology. RAMP …

Pathogen-related signals induce a number of cytosolic pattern-recognition receptors (PRRs)
to form canonical inflammasomes, which activate pro-caspase-1 and trigger pyroptotic cell …

Proteomics, or the large‐scale study of proteomes, has benefitted from many recent advances
in chemical biology, mass spectrometry, and machine learning. The Proteomics in Cell …