User profiles for Jeffrey Drazen

Jeffrey M. Drazen

Professor, Harvard Medical School
Verified email at nejm.org
Cited by 73908

Global strategy for asthma management and prevention: GINA executive summary

…, PJ Barnes, J Bousquet, JM Drazen… - European …, 2008 - Eur Respiratory Soc
Asthma is a serious health problem throughout the world. During the past two decades, many
scientific advances have improved our understanding of asthma and ability to manage and …

Clinical trial registration: a statement from the International Committee of Medical Journal Editors

C De Angelis, JM Drazen, FA Frizelle, C Haug, J Hoey… - The Lancet, 2004 - thelancet.com
In today’s Lancet, the INTERHEART study investigators report a well-coordinated study of
risk factors for myocardial infarction in multiple populations. They present hazard ratios and …

Global Initiative for Asthma Strategy 2021: executive summary and rationale for key changes

…, R Buhl, AA Cruz, L Duijts, JM Drazen… - American journal of …, 2022 - atsjournals.org
The Global Initiative for Asthma (GINA) Strategy Report provides clinicians with an annually
updated evidence-based strategy for asthma management and prevention, which can be …

Artificial intelligence and machine learning in clinical medicine, 2023

CJ Haug, JM Drazen - New England Journal of Medicine, 2023 - Mass Medical Soc
AI and Machine Learning in Clinical Medicine, 2023 This first article in a series describes the
history of artificial intelligence in medicine; the use of AI in image analysis, identification of …

[HTML][HTML] Statistics in medicine—reporting of subgroup analyses in clinical trials

…, JH Ware, DJ Hunter, JM Drazen - … England Journal of …, 2007 - Mass Medical Soc
The analysis of subgroups is often used as a way to glean additional information from data
sets. The strengths and weaknesses of this approach and new Journal policies concerning …

The biology of nitrogen oxides in the airways.

B Gaston, JM Drazen, J Loscalzo… - American journal of …, 1994 - atsjournals.org
Nitrogen oxides (NOx), regarded in the past primarily as toxic air pollutants, have recently
been shown to be bioactive species formed endogenously in the human lung. The relationship …

Treatment of asthma with drugs modifying the leukotriene pathway

JM Drazen, E Israel, PM O'Byrne - New England Journal of …, 1999 - Mass Medical Soc
In 1979 and 1980, the chemical structures of the material previously known as slow-reacting
substance of anaphylaxis were elucidated as 5(S)- hydroxy- 6(R)-glutathionyl- 7,9-trans-11,…

Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma

…, B Chowdhury, KF Chung, R Dahl, JM Drazen… - Journal of Allergy and …, 2010 - Elsevier
Asthma is a global health problem affecting around 300 million individuals of all ages, ethnic
groups and countries. It is estimated that around 250,000 people die prematurely each year …

A summary of the new GINA strategy: a roadmap to asthma control

…, LP Boulet, AA Cruz, JM Drazen… - European …, 2015 - Eur Respiratory Soc
Over the past 20 years, the Global Initiative for Asthma (GINA) has regularly published and
annually updated a global strategy for asthma management and prevention that has formed …

Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet

…, K Ackerman, K Haley, PR Galle, SJ Szabo, JM Drazen… - Science, 2002 - science.org
Human asthma is associated with airway infiltration by T helper 2 (T H 2) lymphocytes. We
observed reduced expression of the T H 1 transcription factor, T-bet, in T cells from airways of …