User profiles for Johan Garssen

johan garssen

utrecht university nutricia research WUN -inflame pharma-nutrition eureka institute UIPS
Verified email at uu.nl
Cited by 29952

[HTML][HTML] The interplay between the gut microbiome and the immune system in the context of infectious diseases throughout life and the role of nutrition in optimizing …

SP Wiertsema, J van Bergenhenegouwen, J Garssen… - Nutrients, 2021 - mdpi.com
Infectious diseases and infections remain a leading cause of death in low-income countries
and a major risk to vulnerable groups, such as infants and the elderly. The immune system …

[HTML][HTML] Pro-and anti-inflammatory effects of short chain fatty acids on immune and endothelial cells

…, BCAM van Esch, GTM Wagenaar, J Garssen… - European journal of …, 2018 - Elsevier
In the gastro-intestinal tract, short chain fatty acids (SCFAs) have protective effects on
epithelial cells. However, their effects on inflammatory cytokine production by endothelial and …

[HTML][HTML] Exploring Braak's hypothesis of Parkinson's disease

CD Rietdijk, P Perez-Pardo, J Garssen… - Frontiers in …, 2017 - frontiersin.org
Parkinson’s disease (PD) is a neurodegenerative disorder for which there is no cure. Most
patients suffer from sporadic PD, which is likely caused by a combination of genetic and …

Altered gut microbiota and activity in a murine model of autism spectrum disorders

…, J Lambert, J Knol, J Garssen… - Brain, behavior, and …, 2014 - Elsevier
Autism spectrum disorder (ASD) is a heterogeneous group of complex neurodevelopmental
disorders with evidence of genetic predisposition. Intestinal disturbances are reported in …

Role of TLR4 in the gut-brain axis in Parkinson's disease: a translational study from men to mice

…, SJ Green, JH Kordower, KM Shannon, J Garssen… - Gut, 2019 - gut.bmj.com
Objective Recent evidence suggesting an important role of gut-derived inflammation in brain
disorders has opened up new directions to explore the possible role of the gut-brain axis in …

Galacto‐oligosaccharides and long‐chain fructo‐oligosaccharides as prebiotics in infant formulas: a review

S Fanaro, G Boehm, J Garssen, J Knol… - Acta …, 2005 - Wiley Online Library
The present review summarizes clinical and experimental data concerning the possible
effects of a prebiotic mixture of short‐chain galacto‐oligosaccharides and long‐chain fructo‐…

Chemotherapy: a double-edged sword in cancer treatment

…, P Khani, A Hosseini, J Garssen… - Cancer immunology …, 2022 - Springer
Chemotherapy is a well-known and effective treatment for different cancers; unfortunately, it
has not been as efficient in the eradication of all cancer cells as been expected. The …

Recovery of extracellular vesicles from human breast milk is influenced by sample collection and vesicle isolation procedures

…, FA Redegeld, J Garssen… - Journal of …, 2014 - Taylor & Francis
Extracellular vesicles (EV) in breast milk carry immune relevant proteins and could play an
important role in the instruction of the neonatal immune system. To further analyze these EV …

[HTML][HTML] Shaping the gut microbiota by breastfeeding: the gateway to allergy prevention?

LWJ Van den Elsen, J Garssen, R Burcelin… - Frontiers in …, 2019 - frontiersin.org
Evidence is accumulating that demonstrates the importance of the gut microbiota in health
and diseases such as allergy. Recent studies emphasize the importance of the ‘window of …

Pathways underlying the gut-to-brain connection in autism spectrum disorders as future targets for disease management

…, J Wu, SL Da Silva, PJ Kamphuis, J Garssen… - European journal of …, 2011 - Elsevier
Autism spectrum disorders (ASDs) are pervasive neurodevelopmental disorders, characterized
by impairments in social interaction and communication and the presence of limited, …